Module

Uitkomst raming

Toelichting

Module Diagnostiek cardiovasculaire complicaties bij kinderen bij MD1

geen financiële gevolgen

Uit de toetsing volgt dat de aanbeveling(en) niet breed toepasbaar zijn (<5.000 patiënten) en daarom naar verwachting geen substantiële financiële gevolgen zal hebben voor de collectieve uitgaven.

Cluster/richtlijn: Cluster myopathie - UV3 Myotone dystrofie Diagnose cardiale complicaties

Uitgangsvraag/modules: Hoe dient de cardiologische zorg bij MD1 eruit te zien?

Database(s): Embase.com, Ovid/Medline

Datum: 4 november 2024

Periode: vanaf 2011

Talen: geen restrictie

Literatuurspecialist: Esther van der Bijl

Rayyan review:  https://new.rayyan.ai/reviews/1214844/overview

BMI-zoekblokken: voor verschillende opdrachten wordt (deels) gebruik gemaakt van de zoekblokken van BMI-Online https://blocks.bmi-online.nl/

Deduplication: voor het ontdubbelen is gebruik gemaakt van http://dedupendnote.nl:9777/

Toelichting:

Voor deze vraag is gezocht op de ‘elementen myotonic dystrophy’ EN ‘cardiovascular disease’ EN ‘MRI, diagnostiek, biomarkers, EFO’.

De volgende sleutelartikelen worden gevonden met deze search:

• Clinical Care Recommendations for Cardiologists Treating Adults With Myotonic Dystrophy | Journal of the American Heart Association (ahajournals.org)
• Bucci 2018: A 34-year longitudinal study on long-term cardiac outcomes in DM1 patients with normal ECG at baseline at an Italian clinical centre PMID: 29429070
• Valaperta 2017:  Cardiac involvement in myotonic dystrophy: The role of troponins and N-terminal pro B-type natriuretic peptide. PMID: 29121498
• Mathew Stokes 2019: Clinical and genetic characteristics of childhood-onset myotonic dystrophy
• PMID: 31520483
• Electrocardiographic predictors of infrahissian conduction disturbances in myotonic dystrophy type 1. Europace 2021. PMID: 33150426
• Myotonic dystrophy type 1: A comparison between the adult- and late-onset subtype. PMID: 36484161
• An evaluation of 24 h Holter monitoring in patients with myotonic dystrophy type 1. PMID: 35851806

De volgende sleutelartikelen vallen uit:

• 2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. -> geen abstract in Embase en valt uit op de P in de Index Terms

Te gebruiken voor richtlijntekst:

A systematic literature search was performed by a medical information specialist using the following bibliographic databases: Embase.com and Ovid/Medline. Both databases were searched from 2011 to 4th of November 2024 for systematic reviews, RCTs, observational and other studies. Systematic searches were completed using a combination of controlled vocabulary/subject headings (e.g., Emtree-terms, MeSH) wherever they were available and natural language keywords. The overall search strategy was derived from three primary search concepts: (1) myotonic dystrophy; (2) cardiovascular disease; (3) MRI, diagnostiek, biomarkers, EFO. Duplicates were removed using EndNote software. After deduplication a total of 1932 records were imported for title/abstract screening.

EMBASE

OVID/MEDLINE

Ontdubbeld

SR

71

23

84

RCT

82

89

154

Observationele studies

550

364

766

Subtotaal

1004*

Overige studies

612

520

928

Totaal

1315

996

1932

No.

Query

Results

#1

'myotonic dystrophy'/exp OR (((dystroph* OR atroph*) NEAR/3 myoton*):ti,ab,kw) OR ((('type 1' OR 'type one' OR 'type i') NEAR/3 (dystroph* OR myoton*)):ti,ab,kw) OR steinert*:ti,ab,kw OR 'myoton* myopath*':ti,ab,kw

12682

#2

'cardiovascular disease'/exp OR 'heart conduction'/exp OR 'trinucleotide repeat'/exp OR (('cytosine'/exp OR 'cytosin*':ti,ab,kw) AND ('guanine'/exp OR 'guanine*':ti,ab,kw OR 'quanine*':ti,ab,kw) AND ('thymine'/exp OR 'methacil*':ti,ab,kw OR 'methyluracil*':ti,ab,kw OR 'thymine*':ti,ab,kw OR 'tymine*':ti,ab,kw)) OR (((angiocardiovascular* OR cardiovascular*) NEAR/3 (disease* OR complication* OR disorder* OR disturbance* OR event*)):ti,ab,kw) OR (((cardiac* OR heart* OR myocard*) NEXT/1 (conduction* OR involvement* OR abnormalit* OR death*)):ti,ab,kw) OR (((ctg* OR trinucleotide* OR triplet* OR microsatellite*) NEXT/1 repeat*):ti,ab,kw) OR 'angiocardiopath*':ti,ab,kw

5908423

#3

'nuclear magnetic resonance imaging'/exp OR 'mri scanner'/exp OR ('magnetic resonance':ab,ti AND (image:ab,ti OR images:ab,ti OR imaging:ab,ti)) OR mri:ab,ti OR mris:ab,ti OR nmr:ab,ti OR mra:ab,ti OR mras:ab,ti OR zeugmatograph*:ab,ti OR 'mr tomography':ab,ti OR 'mr tomographies':ab,ti OR 'mr tomographic':ab,ti OR 'mr imag*':ti,ab,kw OR 'proton spin':ab,ti OR ((magneti*:ab,ti OR 'chemical shift':ab,ti) AND imaging:ab,ti) OR fmri:ab,ti OR fmris:ab,ti OR rsfmri:ti,ab,kw OR 'diagnostic procedure'/exp OR 'diagnosis'/exp OR ((diagnostic* NEAR/3 (method* OR procedure* OR technique*)):ti,ab,kw) OR 'diagnosis':ti,ab,kw OR 'biological marker'/exp OR 'amino terminal pro brain natriuretic peptide'/exp OR 'biomarker*':ti,ab,kw OR 'bio* marker*':ti,ab,kw OR 'amino terminal b type natriuretic peptide*':ti,ab,kw OR 'amino terminal pro brain natriuretic peptide*':ti,ab,kw OR 'amino terminal probrain natriuretic peptide*':ti,ab,kw OR 'n terminal pro b type natriuretic peptide*':ti,ab,kw OR 'n terminal pro brain natriuretic peptide*':ti,ab,kw OR 'n terminal probrain natriuretic peptide*':ti,ab,kw OR 'nt-pro-bnp':ti,ab,kw OR 'electrophysiological procedures'/exp OR 'electrocardiography'/exp OR ((electrophysiolog* NEXT/1 (procedure* OR recording* OR technique* OR research*)):ti,ab,kw) OR 'electro cardiograph*':ti,ab,kw OR 'electrocardiograph*':ti,ab,kw OR 'electromyocardiograph*':ti,ab,kw OR 'polycardiograph*':ti,ab,kw

24014909

#4

#1 AND #2 AND #3

3572

#5

#4 AND [2011-2025]/py NOT ('conference abstract'/it OR 'editorial'/it OR 'letter'/it OR 'note'/it) NOT (('animal'/exp OR 'animal experiment'/exp OR 'animal model'/exp OR 'nonhuman'/exp) NOT 'human'/exp)

1315

#6

'meta analysis'/exp OR 'meta analysis (topic)'/exp OR metaanaly*:ti,ab OR 'meta analy*':ti,ab OR metanaly*:ti,ab OR 'systematic review'/de OR 'cochrane database of systematic reviews'/jt OR prisma:ti,ab OR prospero:ti,ab OR (((systemati* OR scoping OR umbrella OR 'structured literature') NEAR/3 (review* OR overview*)):ti,ab) OR ((systemic* NEAR/1 review*):ti,ab) OR (((systemati* OR literature OR database* OR 'data base*') NEAR/10 search*):ti,ab) OR (((structured OR comprehensive* OR systemic*) NEAR/3 search*):ti,ab) OR (((literature NEAR/3 review*):ti,ab) AND (search*:ti,ab OR database*:ti,ab OR 'data base*':ti,ab)) OR (('data extraction':ti,ab OR 'data source*':ti,ab) AND 'study selection':ti,ab) OR ('search strategy':ti,ab AND 'selection criteria':ti,ab) OR ('data source*':ti,ab AND 'data synthesis':ti,ab) OR medline:ab OR pubmed:ab OR embase:ab OR cochrane:ab OR (((critical OR rapid) NEAR/2 (review* OR overview* OR synthes*)):ti) OR ((((critical* OR rapid*) NEAR/3 (review* OR overview* OR synthes*)):ab) AND (search*:ab OR database*:ab OR 'data base*':ab)) OR metasynthes*:ti,ab OR 'meta synthes*':ti,ab

1075326

#7

'clinical trial'/exp OR 'randomization'/exp OR 'single blind procedure'/exp OR 'double blind procedure'/exp OR 'crossover procedure'/exp OR 'placebo'/exp OR 'prospective study'/exp OR rct:ab,ti OR random*:ab,ti OR 'single blind':ab,ti OR 'randomised controlled trial':ab,ti OR 'randomized controlled trial'/exp OR placebo*:ab,ti

4136728

#8

'major clinical study'/de OR 'clinical study'/de OR 'case control study'/de OR 'family study'/de OR 'longitudinal study'/de OR 'retrospective study'/de OR 'prospective study'/de OR 'comparative study'/de OR 'cohort analysis'/de OR ((cohort NEAR/1 (study OR studies)):ab,ti) OR (('case control' NEAR/1 (study OR studies)):ab,ti) OR (('follow up' NEAR/1 (study OR studies)):ab,ti) OR (observational NEAR/1 (study OR studies)) OR ((epidemiologic NEAR/1 (study OR studies)):ab,ti) OR (('cross sectional' NEAR/1 (study OR studies)):ab,ti)

8477803

#9

'case control study'/de OR 'comparative study'/exp OR 'control group'/de OR 'controlled study'/de OR 'controlled clinical trial'/de OR 'crossover procedure'/de OR 'double blind procedure'/de OR 'phase 2 clinical trial'/de OR 'phase 3 clinical trial'/de OR 'phase 4 clinical trial'/de OR 'pretest posttest design'/de OR 'pretest posttest control group design'/de OR 'quasi experimental study'/de OR 'single blind procedure'/de OR 'triple blind procedure'/de OR (((control OR controlled) NEAR/6 trial):ti,ab,kw) OR (((control OR controlled) NEAR/6 (study OR studies)):ti,ab,kw) OR (((control OR controlled) NEAR/1 active):ti,ab,kw) OR 'open label*':ti,ab,kw OR (((double OR two OR three OR multi OR trial) NEAR/1 (arm OR arms)):ti,ab,kw) OR ((allocat* NEAR/10 (arm OR arms)):ti,ab,kw) OR placebo*:ti,ab,kw OR 'sham-control*':ti,ab,kw OR (((single OR double OR triple OR assessor) NEAR/1 (blind* OR masked)):ti,ab,kw) OR nonrandom*:ti,ab,kw OR 'non-random*':ti,ab,kw OR 'quasi-experiment*':ti,ab,kw OR crossover:ti,ab,kw OR 'cross over':ti,ab,kw OR 'parallel group*':ti,ab,kw OR 'factorial trial':ti,ab,kw OR ((phase NEAR/5 (study OR trial)):ti,ab,kw) OR ((case* NEAR/6 (matched OR control*)):ti,ab,kw) OR ((match* NEAR/6 (pair OR pairs OR cohort* OR control* OR group* OR healthy OR age OR sex OR gender OR patient* OR subject* OR participant*)):ti,ab,kw) OR ((propensity NEAR/6 (scor* OR match*)):ti,ab,kw) OR versus:ti OR vs:ti OR compar*:ti OR ((compar* NEAR/1 study):ti,ab,kw) OR (('major clinical study'/de OR 'clinical study'/de OR 'cohort analysis'/de OR 'observational study'/de OR 'cross-sectional study'/de OR 'multicenter study'/de OR 'correlational study'/de OR 'follow up'/de OR cohort*:ti,ab,kw OR 'follow up':ti,ab,kw OR followup:ti,ab,kw OR longitudinal*:ti,ab,kw OR prospective*:ti,ab,kw OR retrospective*:ti,ab,kw OR observational*:ti,ab,kw OR 'cross sectional*':ti,ab,kw OR cross?ectional*:ti,ab,kw OR multicent*:ti,ab,kw OR 'multi-cent*':ti,ab,kw OR consecutive*:ti,ab,kw) AND (group:ti,ab,kw OR groups:ti,ab,kw OR subgroup*:ti,ab,kw OR versus:ti,ab,kw OR vs:ti,ab,kw OR compar*:ti,ab,kw OR 'odds ratio*':ab OR 'relative odds':ab OR 'risk ratio*':ab OR 'relative risk*':ab OR 'rate ratio':ab OR aor:ab OR arr:ab OR rrr:ab OR ((('or' OR 'rr') NEAR/6 ci):ab)))

15512994

#10

#5 AND #6

71

#11

#5 AND #7 NOT #10

82

#12

#5 AND (#8 OR #9) NOT (#10 OR #11)

550

#13

#5 NOT (#10 OR #11 OR #12)

612

#14

#10 OR #11 OR #12 OR #13

1315

#

Searches

Results

1

exp Myotonic Dystrophy/ or ((dystroph* or atroph*) adj3 myoton*).ti,ab,kf. or ((type 1 or type one or type i) adj3 (dystroph* or myoton*)).ti,ab,kf. or steinert*.ti,ab,kf. or muscular* dystroph*.ti,ab,kf. or myoton* myopath*.ti,ab,kf.

36298

2

exp Cardiovascular Diseases/ or exp Trinucleotide Repeats/ or ((exp Cytosine/ or cytosin*.ti,ab,kf.) and (exp Guanine/ or guanine*.ti,ab,kf. or quanine*.ti,ab,kf.) and (exp Thymine/ or methacil*.ti,ab,kf. or methyluracil*.ti,ab,kf. or thymine*.ti,ab,kf. or tymine*.ti,ab,kf.)) or ((angiocardiovascular* or cardiovascular*) adj3 (disease* or complication* or disorder* or disturbance* or event*)).ti,ab,kf. or ((cardiac* or heart* or myocard*) adj1 (conduction* or involvement* or abnormalit* or death*)).ti,ab,kf. or ((ctg* or trinucleotide* or triplet* or microsatellite*) adj1 repeat*).ti,ab,kf. or angiocardiopath*.ti,ab,kf.

2996023

3

exp magnetic resonance imaging/ or ("magnetic resonance" and (image or images or imaging)).ti,ab,kf. or mri.ti,ab,kf. or mris.ti,ab,kf. or nmr.ti,ab,kf. or mra.ti,ab,kf. or mras.ti,ab,kf. or zeugmatograph*.ti,ab,kf. or "mr tomography".ti,ab,kf. or "mr tomographies".ti,ab,kf. or "mr tomographic".ti,ab,kf. or 'mr imag*'.ti,ab,kf. or "proton spin".ti,ab,kf. or ((magneti* or "chemical shift") and imaging).ti,ab,kf. or fmri.ti,ab,kf. or fmris.ti,ab,kf. or rsfmri.ti,ab,kf. or exp Diagnostic Techniques, Cardiovascular/ or exp Diagnostic Tests, Routine/ or exp Diagnosis/ or (diagnostic* adj3 (method* or procedure* or technique*)).ti,ab,kf. or diagnosis.ti,ab,kf. or exp Biomarkers/ or biomarker*.ti,ab,kf. or bio* marker*.ti,ab,kf. or amino terminal b type natriuretic peptide*.ti,ab,kf. or amino terminal pro brain natriuretic peptide*.ti,ab,kf. or amino terminal probrain natriuretic peptide*.ti,ab,kf. or n terminal pro b type natriuretic peptide*.ti,ab,kf. or n terminal pro brain natriuretic peptide*.ti,ab,kf. or n terminal probrain natriuretic peptide*.ti,ab,kf. or nt pro bnp.ti,ab,kf. or exp Electrophysiologic Techniques, Cardiac/ or exp Electrocardiography/ or Electrodiagnosis/ or (electrophysiolog* adj1 (procedure* or recording* or technique* or research*)).ti,ab,kf. or electro cardiograph*.ti,ab,kf. or electrocardiograph*.ti,ab,kf. or electromyocardiograph*.ti,ab,kf. or polycardiograph*.ti,ab,kf.

11660749

4

1 and 2 and 3

2554

5

limit 4 to yr="2011 -Current"

1135

6

5 not (comment/ or editorial/ or letter/) not ((exp animals/ or exp models, animal/) not humans/)

996

7

meta-analysis/ or meta-analysis as topic/ or (metaanaly* or meta-analy* or metanaly*).ti,ab,kf. or systematic review/ or cochrane.jw. or (prisma or prospero).ti,ab,kf. or ((systemati* or scoping or umbrella or "structured literature") adj3 (review* or overview*)).ti,ab,kf. or (systemic* adj1 review*).ti,ab,kf. or ((systemati* or literature or database* or data-base*) adj10 search*).ti,ab,kf. or ((structured or comprehensive* or systemic*) adj3 search*).ti,ab,kf. or ((literature adj3 review*) and (search* or database* or data-base*)).ti,ab,kf. or (("data extraction" or "data source*") and "study selection").ti,ab,kf. or ("search strategy" and "selection criteria").ti,ab,kf. or ("data source*" and "data synthesis").ti,ab,kf. or (medline or pubmed or embase or cochrane).ab. or ((critical or rapid) adj2 (review* or overview* or synthes*)).ti. or (((critical* or rapid*) adj3 (review* or overview* or synthes*)) and (search* or database* or data-base*)).ab. or (metasynthes* or meta-synthes*).ti,ab,kf.

786636

8

exp clinical trial/ or randomized controlled trial/ or exp clinical trials as topic/ or randomized controlled trials as topic/ or Random Allocation/ or Double-Blind Method/ or Single-Blind Method/ or (clinical trial, phase i or clinical trial, phase ii or clinical trial, phase iii or clinical trial, phase iv or controlled clinical trial or randomized controlled trial or multicenter study or clinical trial).pt. or random*.ti,ab. or (clinic* adj trial*).tw. or ((singl* or doubl* or treb* or tripl*) adj (blind$3 or mask$3)).tw. or Placebos/ or placebo*.tw.

2799343

9

Epidemiologic studies/ or case control studies/ or exp cohort studies/ or Controlled Before-After Studies/ or Case control.tw. or cohort.tw. or Cohort analy$.tw. or (Follow up adj (study or studies)).tw. or (observational adj (study or studies)).tw. or Longitudinal.tw. or Retrospective*.tw. or prospective*.tw. or consecutive*.tw. or Cross sectional.tw. or Cross-sectional studies/ or historically controlled study/ or interrupted time series analysis/ [Onder exp cohort studies vallen ook longitudinale, prospectieve en retrospectieve studies]

4870750

10

Case-control Studies/ or clinical trial, phase ii/ or clinical trial, phase iii/ or clinical trial, phase iv/ or comparative study/ or control groups/ or controlled before-after studies/ or controlled clinical trial/ or double-blind method/ or historically controlled study/ or matched-pair analysis/ or single-blind method/ or (((control or controlled) adj6 (study or studies or trial)) or (compar* adj (study or studies)) or ((control or controlled) adj1 active) or "open label*" or ((double or two or three or multi or trial) adj (arm or arms)) or (allocat* adj10 (arm or arms)) or placebo* or "sham-control*" or ((single or double or triple or assessor) adj1 (blind* or masked)) or nonrandom* or "non-random*" or "quasi-experiment*" or "parallel group*" or "factorial trial" or "pretest posttest" or (phase adj5 (study or trial)) or (case* adj6 (matched or control*)) or (match* adj6 (pair or pairs or cohort* or control* or group* or healthy or age or sex or gender or patient* or subject* or participant*)) or (propensity adj6 (scor* or match*))).ti,ab,kf. or (confounding adj6 adjust*).ti,ab. or (versus or vs or compar*).ti. or ((exp cohort studies/ or epidemiologic studies/ or multicenter study/ or observational study/ or seroepidemiologic studies/ or (cohort* or 'follow up' or followup or longitudinal* or prospective* or retrospective* or observational* or multicent* or 'multi-cent*' or consecutive*).ti,ab,kf.) and ((group or groups or subgroup* or versus or vs or compar*).ti,ab,kf. or ('odds ratio*' or 'relative odds' or 'risk ratio*' or 'relative risk*' or aor or arr or rrr).ab. or (("OR" or "RR") adj6 CI).ab.))

5824694

11

6 and 7

23

12

(6 and 8) not 11

89

13

(6 and (9 or 10)) not (11 or 12)

364

14

6 not (11 or 12 or 13)

520

15

11 or 12 or 13 or 14

996