Bacteriële CZS infecties

Initiatief: SWAB Aantal modules: 9

Startpagina - Bacteriële CZS infecties

Waar gaat deze richtlijn over?

Deze richtlijn richt zich op wat volgens de huidige maatstaven de beste zorg is voor patiënten met een bacteriële infectie van het centraal zenuwstelsel. In de richtlijn komen de volgende onderwerpen aan de orde:

    • Binnen dan wel buiten het ziekenhuis opgelopen hersenvliesontsteking
    • De behandeling van een hersenvliesontsteking die na een operatie is ontstaan
    • De behandeling via een ventriculaire drain
    • De duur van de behandeling voordat een ventriculaire drain kan worden vervangen
    • Het ontstaan van een holte met pus (abces)

 

Voor wie is de richtlijn bedoeld?

Deze richtlijn is bestemd voor alle zorgverleners die betrokken zijn bij de zorg voor patiënten met een bacteriële infectie van het centraal zenuwstelsel.

 

Voor patiënten

CZS is de afkorting voor het centraal zenuwstelsel. Tot het centraal zenuwstelsel behoren de hersenen en het ruggenmerg. Om de hersenen en het ruggenmerg zit een dun vlies. Dit vlies heeft een beschermende functie en wordt het hersenvlies genoemd. Als er een infectie ontstaat in het centraal zenuwstelsel is het voor de behandeling soms nodig om een dun slangetje in de ruimte binnen dit vlies aan te brengen. Dit wordt een ventriculaire drain genoemd. Een infectie van de hersenen en/of het ruggenmerg kan verschillende oorzaken hebben. Als een bacterie de oorzaak is, wordt dit een bacteriële CZS infectie genoemd. Hoe vaak dit precies voorkomt is niet bekend.

 

Meer informatie over hersenvliesontsteking is te vinden op de website van de patiëntenvereniging:

http://www.meningitis-stichting.nl/ziekte-informatie/meningitis

 

Hoe is de richtlijn tot stand gekomen?

Het initiatief voor deze richtlijn is afkomstig van de Stichting Werkgroep Antibioticabeleid (SWAB). De richtlijn is opgesteld door een multidisciplinaire commissie met vertegenwoordigers vanuit de kinderartsen, internist-infectiologen, medisch microbiologen, neurochirurgen en neurologen. 

 

Onderbouwing

  1. CBO. Kwaliteitsinstituut voor de Gezondheidszorg CBO, Handleiding voor werkgroepleden. http://www.cbo.nl/Downloads/222/EBRO_handl_totaal.pdf
  2. van de Beek D, Weisfelt M, de Gans J, Tunkel AR, Wijdicks EF. Drug Insight: adjunctive therapies in adults with bacterial meningitis. Nat Clin Pract Neurol 2006; 2: 504-16.
  3. van de Beek D, Brouwer MC, de Gans J et al. Richtlijn bacteriele meningitis. Utrecht: Nederlandse Vereniging voor Neurologie; 2011.
  4. van de Beek D, Drake JM, Tunkel AR. Nosocomial bacterial meningitis. N Engl J Med 2010; 362: 146-54.
  5. Bohr V, Rasmussen N, Hansen B et al. 875 cases of bacterial meningitis: diagnostic procedures and the impact of preadmission antibiotic therapy. Part III of a three-part series. J Infect 1983; 7: 193-202.
  6. Brouwer MC, Tunkel AR, van de Beek D. Epidemiology, diagnosis, and antimicrobial treatment of acute bacterial meningitis. Clin Microbiol Rev 2010; 23: 467-92.
  7. Spanos A, Harrell FE, Jr., Durack DT. Differential diagnosis of acute meningitis. An analysis of the predictive value of initial observations. JAMA 1989; 262: 2700-7.
  8. Tunkel AR. Brain abscess. In: Mandell GL, Bennett JE, Dolin R, editors. Principles and practive of infectious diseases. 7 ed. Philadelphia: Churchill livingstone; 2010. p. 1265-78.
  9. Kastenbauer S, Pfister HW, Wispelwey B, Scheld WM. Brain abscess. In: Scheld WM, Whitley RJ, Marra CM, editors. Infections of the central nervous system. 3 ed. Philadelphia: Lippincott Williams & Wilkins; 2004. p. 479-507.
  10. van de Beek D, de Gans J, Spanjaard L, Weisfelt M, Reitsma JB, Vermeulen M. Clinical features and prognostic factors in adults with bacterial meningitis. N Engl J Med 2004; 351: 1849-59.
  11. Brouwer MC, Heckenberg SG, de GJ, Spanjaard L, Reitsma JB, van de Beek D. Nationwide implementation of adjunctive dexamethasone therapy for pneumococcal meningitis. Neurology 2010.
  12. van de Beek D, de Gans J, Tunkel AR, Wijdicks EF. Community-acquired bacterial meningitis in adults. N Engl J Med 2006; 354: 44-53.
  13. Garges HP, Moody MA, Cotten CM et al. Neonatal meningitis: what is the correlation among cerebrospinal fluid cultures, blood cultures, and cerebrospinal fluid parameters? Pediatrics 2006; 117: 1094-100.
  14. Hristeva L, Booy R, Bowler I, Wilkinson AR. Prospective surveillance of neonatal meningitis. Arch Dis Child 1993; 69: 14-8.
  15. Holt DE, Halket S, de LJ, Harvey D. Neonatal meningitis in England and Wales: 10 years on. Arch Dis Child Fetal Neonatal Ed 2001; 84: F85-F89.
  16. Galiza EP, Heath PT. Improving the outcome of neonatal meningitis. Curr Opin Infect Dis 2009; 22: 229-34.
  17. Heath PT, Nik Yusoff NK, Baker CJ. Neonatal meningitis. Arch Dis Child Fetal Neonatal Ed 2003; 88: F173-F178.
  18. Siegal T, Pfeffer MR, Steiner I. Antibiotic therapy for infected Ommaya reservoir systems. Neurosurgery 1988; 22: 97-100.
  19. Cooper MD, Keeney RE, Lyons SF, Cheatle EL. Synergistic effects of ampicillin-aminoglycoside combinations on group B streptococci. Antimicrob Agents Chemother 1979; 15: 484-6.
  20. Netherlands Reference Laboratory for Bacterial Meningitis (AMC/RIVM). Bacterial meningitis in the Netherlands Annual report 2010. Amsterdam: University of Amsterdam; 2011.
  21. Odio CM, Puig JR, Feris JM et al. Prospective, randomized, investigator-blinded study of the efficacy and safety of meropenem vs. cefotaxime therapy in bacterial meningitis in children. Meropenem Meningitis Study Group. Pediatr Infect Dis J 1999; 18: 581-90.
  22. Brouwer MC, Heckenberg SG, de Gans J, Spanjaard L, Reitsma JB, van de Beek D. Nationwide implementation of adjunctive dexamethasone therapy for pneumococcal meningitis. Neurology 2010; 75: 1533-9.
  23. Heckenberg SG, de Gans J, Brouwer MC et al. Clinical features, outcome, and meningococcal genotype in 258 adults with meningococcal meningitis: a prospective cohort study. Medicine (Baltimore) 2008; 87: 185-92.
  24. Brouwer MC, van de Beek D, Heckenberg SG, Spanjaard L, de Gans J. Community-acquired Listeria monocytogenes meningitis in adults. Clin Infect Dis 2006; 43: 1233-8.
  25. Karageorgopoulos DE, Valkimadi PE, Kapaskelis A, Rafailidis PI, Falagas ME. Short versus long duration of antibiotic therapy for bacterial meningitis: a meta-analysis of randomised controlled trials in children. Arch Dis Child 2009; 94: 607-14.
  26. van de Beek D, Brouwer MC. No difference between short-course and long-course antibiotics for bacterial meningitis in children, but available evidence limited. Evid Based Med 2010; 15: 6-7.
  27. Molyneux E, Nizami SQ, Saha S et al. 5 versus 10 days of treatment with ceftriaxone for bacterial meningitis in children: a double-blind randomised equivalence study. Lancet 2011; 377: 1837-45.
  28. Tunkel AR, Hartman BJ, Kaplan SL et al. Practice guidelines for the management of bacterial meningitis. Clin Infect Dis 2004; 39: 1267-84.
  29. van der Meer H, van ZA, Spanjaard L, Van FM. [An infant with meningitis caused by resistant pneumococcus: infection despite vaccination]. Ned Tijdschr Geneeskd 2012; 156: A3806.
  30. Mitja O, Pigrau C, Ruiz I et al. Predictors of mortality and impact of aminoglycosides on outcome in listeriosis in a retrospective cohort study. J Antimicrob Chemother 2009; 64: 416-23.
  31. Lorber B. Listeriosis. Clin Infect Dis 1997; 24: 1-9.
  32. Red Book: 2009 report of the committee on infectious diseases. 28 ed. Elk Grove Village, IL, USA: American Academy of Pediatrics; 2009.
  33. Falagas ME, Bliziotis IA, Tam VH. Intraventricular or intrathecal use of polymyxins in patients with Gram-negative meningitis: a systematic review of the available evidence. Int J Antimicrob Agents 2007; 29: 9-25.
  34. Lozier AP, Sciacca RR, Romagnoli MF, Connolly ES, Jr. Ventriculostomy-related infections: a critical review of the literature. Neurosurgery 2008; 62 Suppl 2: 688-700.
  35. Mayhall CG, Archer NH, Lamb VA et al. Ventriculostomy-related infections. A prospective epidemiologic study. N Engl J Med 1984; 310: 553-9.
  36. Stenager E, Gerner-Smidt P, Kock-Jensen C. Ventriculostomy-related infections--an epidemiological study. Acta Neurochir (Wien ) 1986; 83: 20-3.
  37. Coplin WM, Avellino AM, Kim DK, Winn HR, Grady MS. Bacterial meningitis associated with lumbar drains: a retrospective cohort study. J Neurol Neurosurg Psychiatry 1999; 67: 468-73.
  38. Lyke KE, Obasanjo OO, Williams MA, O'Brien M, Chotani R, Perl TM. Ventriculitis complicating use of intraventricular catheters in adult neurosurgical patients. Clin Infect Dis 2001; 33: 2028-33.
  39. Wong GK, Poon WS, Wai S, Yu LM, Lyon D, Lam JM. Failure of regular external ventricular drain exchange to reduce cerebrospinal fluid infection: result of a randomised controlled trial. J Neurol Neurosurg Psychiatry 2002; 73: 759-61.
  40. Pfisterer W, Muhlbauer M, Czech T, Reinprecht A. Early diagnosis of external ventricular drainage infection: results of a prospective study. J Neurol Neurosurg Psychiatry 2003; 74: 929-32.
  41. Park P, Garton HJ, Kocan MJ, Thompson BG. Risk of infection with prolonged ventricular catheterization. Neurosurgery 2004; 55: 594-9.
  42. Arabi Y, Memish ZA, Balkhy HH et al. Ventriculostomy-associated infections: incidence and risk factors. Am J Infect Control 2005; 33: 137-43.
  43. Schade RP, Schinkel J, Visser LG, Van Dijk JM, Voormolen JH, Kuijper EJ. Bacterial meningitis caused by the use of ventricular or lumbar cerebrospinal fluid catheters. J Neurosurg 2005; 102: 229-34.
  44. Ohrstrom JK, Skou JK, Ejlertsen T, Kosteljanetz M. Infected ventriculostomy: bacteriology and treatment. Acta Neurochir (Wien ) 1989; 100: 67-9.
  45. Vinchon M, Dhellemmes P. Cerebrospinal fluid shunt infection: risk factors and long-term follow-up. Childs Nerv Syst 2006; 22: 692-7.
  46. Conen A, Walti LN, Merlo A, Fluckiger U, Battegay M, Trampuz A. Characteristics and treatment outcome of cerebrospinal fluid shunt-associated infections in adults: a retrospective analysis over an 11year period. Clin Infect Dis 2008; 47: 73-82.
  47. Walters BC, Hoffman HJ, Hendrick EB, Humphreys RP. Cerebrospinal fluid shunt infection. Influences on initial management and subsequent outcome. J Neurosurg 1984; 60: 1014-21.
  48. Filka J, Huttova M, Tuharsky J, Sagat T, Kralinsky K, Krcmery V, Jr. Nosocomial meningitis in children after ventriculoperitoneal shunt insertion. Acta Paediatr 1999; 88: 576-8.
  49. Kestle JR, Garton HJ, Whitehead WE et al. Management of shunt infections: a multicenter pilot study. J Neurosurg 2006; 105: 177-81.
  50. Sacar S, Turgut H, Toprak S et al. A retrospective study of central nervous system shunt infections diagnosed in a university hospital during a 4-year period. BMC Infect Dis 2006; 6:43.: 43.
  51. Korinek AM, Baugnon T, Golmard JL, van Effenterre R, Coriat P, Puybasset L. Risk factors for adult nosocomial meningitis after craniotomy: role of antibiotic prophylaxis. Neurosurgery 2008; 62 Suppl 2: 532-9.
  52. McClelland S, III, Hall WA. Postoperative central nervous system infection: incidence and associated factors in 2111 neurosurgical procedures. Clin Infect Dis 2007; 45: 55-9.
  53. Aucoin PJ, Kotilainen HR, Gantz NM, Davidson R, Kellogg P, Stone B. Intracranial pressure monitors. Epidemiologic study of risk factors and infections. Am J Med 1986; 80: 369-76.
  54. Kourbeti IS, Jacobs AV, Koslow M, Karabetsos D, Holzman RS. Risk factors associated with postcraniotomy meningitis. Neurosurgery 2007; 60: 317-25.
  55. Federico G, Tumbarello M, Spanu T et al. Risk factors and prognostic indicators of bacterial meningitis in a cohort of 3580 postneurosurgical patients. Scand J Infect Dis 2001; 33: 533-7.
  56. Wang KW, Chang WN, Huang CR et al. Post-neurosurgical nosocomial bacterial meningitis in adults: microbiology, clinical features, and outcomes. J Clin Neurosci 2005; 12: 647-50.
  57. Zarrouk V, Vassor I, Bert F et al. Evaluation of the management of postoperative aseptic meningitis. Clin Infect Dis 2007; 44: 1555-9.
  58. Baltas I, Tsoulfa S, Sakellariou P, Vogas V, Fylaktakis M, Kondodimou A. Posttraumatic meningitis: bacteriology, hydrocephalus, and outcome. Neurosurgery 1994; 35: 422-6.
  59. Infection in neurosurgery working party of the british society for antimicrobial chemotherapy. The management of neurosurgical patients with postoperative bacterial or aseptic meningitis or external ventricular drain-associated ventriculitis. Infection in Neurosurgery Working Party of the British Society for Antimicrobial Chemotherapy. Br J Neurosurg 2000; 14: 7-12.
  60. Schreffler RT, Schreffler AJ, Wittler RR. Treatment of cerebrospinal fluid shunt infections: a decision analysis. Pediatr Infect Dis J 2002; 21: 632-6.
  61. Kim BN, Peleg AY, Lodise TP et al. Management of meningitis due to antibiotic-resistant Acinetobacter species. Lancet Infect Dis 2009; 9: 245-55.
  62. Pfausler B, Spiss H, Beer R et al. Treatment of staphylococcal ventriculitis associated with external cerebrospinal fluid drains: a prospective randomized trial of intravenous compared with intraventricular vancomycin therapy. J Neurosurg 2003; 98: 1040-4.
  63. Beller AJ, Sahar A, Praiss I. Brain abscess. Review of 89 cases over a period of 30 years. J Neurol Neurosurg Psychiatry 1973; 36: 757-68.
  64. Berlit P, Fedel C, Tornow K, Schmiedek P. [Bacterial brain abscess--experiences with 67 patients]. Fortschr Neurol Psychiatr 1996; 64: 297-306.
  65. Carpenter J, Stapleton S, Holliman R. Retrospective analysis of 49 cases of brain abscess and review of the literature. Eur J Clin Microbiol Infect Dis 2007; 26: 1-11.
  66. Hakan T, Ceran N, Erdem I, Berkman MZ, Goktas P. Bacterial brain abscesses: an evaluation of 96 cases. J Infect 2006; 52: 359-66.
  67. Tattevin P, Bruneel F, Clair B et al. Bacterial brain abscesses: a retrospective study of 94 patients admitted to an intensive care unit (1980 to 1999). Am J Med 2003; 115: 143-6.
  68. Smith SJ, Ughratdar I, MacArthur DC. Never go to sleep on undrained pus: a retrospective review of surgery for intraparenchymal cerebral abscess. Br J Neurosurg 2009; 23: 412-7.
  69. Al Masalma M, Armougom F, Scheld WM et al. The expansion of the microbiological spectrum of brain abscesses with use of multiple 16S ribosomal DNA sequencing. Clin Infect Dis 2009; 48: 1169-78.
  70. de Lastours V, Kalamarides M, Leflon V et al. Optimization of bacterial diagnosis yield after needle aspiration in immunocompetent adults with brain abscesses. Neurosurgery 2008; 63: 362-7.
  71. Cavusoglu H, Kaya RA, Turkmenoglu ON, Colak I, Aydin Y. Brain abscess: analysis of results in a series of 51 patients with a combined surgical and medical approach during an 11-year period. Neurosurg Focus 2008; 24: E9.
  72. Goodkin HP, Harper MB, Pomeroy SL. Intracerebral abscess in children: historical trends at Children's Hospital Boston. Pediatrics 2004; 113: 1765-70.
  73. Le Moal G, Landron C, Grollier G et al. Characteristics of brain abscess with isolation of anaerobic bacteria. Scand J Infect Dis 2003; 35: 318-21.
  74. Sennaroglu L, Sozeri B. Otogenic brain abscess: review of 41 cases. Otolaryngol Head Neck Surg 2000; 123: 751-5.
  75. Barlas O, Sencer A, Erkan K, Eraksoy H, Sencer S, Bayindir C. Stereotactic surgery in the management of brain abscess. Surg Neurol 1999; 52: 404-10.
  76. Mamelak AN, Mampalam TJ, Obana WG, Rosenblum ML. Improved management of multiple brain abscesses: a combined surgical and medical approach. Neurosurgery 1995; 36: 76-85.
  77. O'Donoghue MA, Green HT, Shaw MD. Cerebral abscess on Merseyside 1980-1988. J Infect 1992; 25: 163-72.
  78. Tekkok IH, Erbengi A. Management of brain abscess in children: review of 130 cases over a period of 21 years. Childs Nerv Syst 1992; 8: 411-6.
  79. Renier D, Flandin C, Hirsch E, Hirsch JF. Brain abscesses in neonates. A study of 30 cases. J Neurosurg 1988; 69: 877-82.
  80. Chun CH, Johnson JD, Hofstetter M, Raff MJ. Brain abscess. A study of 45 consecutive cases. Medicine (Baltimore) 1986; 65: 415-31.
  81. Brook I. Bacteriology of intracranial abscess in children. J Neurosurg 1981; 54: 484-8.
  82. Shahzad K, Hamid MH, Khan MA, Malik N, Maqbool S. Brain abscess in children. J Coll Physicians Surg Pak 2005; 15: 609-11.
  83. de Louvois, ., Gortavai P, Hurley R. Bacteriology of abscesses of the central nervous system: a multicentre prospective study. Br Med J 1977; 2: 981-4.
  84. Jansson AK, Enblad P, Sjolin J. Efficacy and safety of cefotaxime in combination with metronidazole for empirical treatment of brain abscess in clinical practice: a retrospective study of 66 consecutive cases. Eur J Clin Microbiol Infect Dis 2004; 23: 7-14.
  85. Bartt R. Listeria and atypical presentations of Listeria in the central nervous system. Semin Neurol 2000; 20: 361-73.
  86. Roche M, Humphreys H, Smyth E et al. A twelve-year review of central nervous system bacterial abscesses; presentation and aetiology. Clin Microbiol Infect 2003; 9: 803-9.
  87. Mampalam TJ, Rosenblum ML. Trends in the management of bacterial brain abscesses: a review of 102 cases over 17 years. Neurosurgery 1988; 23: 451-8.
  88. Bagdatoglu H, Ildan F, Cetinalp E et al. The clinical presentation of intracranial abscesses. A study of seventy-eight cases. J Neurosurg Sci 1992; 36: 139-43.
  89. Miller ES, Dias PS, Uttley D. CT scanning in the management of intracranial abscess: a review of 100 cases. Br J Neurosurg 1988; 2: 439-46.
  90. Tonon E, Scotton PG, Gallucci M, Vaglia A. Brain abscess: clinical aspects of 100 patients. Int J Infect Dis 2006; 10: 103-9.
  91. Gomez J, Garcia-Vazquez E, Martinez PM et al. [Brain abscess. The experience of 30 years]. Med Clin (Barc ) 2008; 130: 736-9.
  92. Lunardi P, Acqui M, Ferrante L, Mastronardi L, Fortuna A. Non-traumatic brain abscess. Neurosurg Rev 1993; 16: 189-96.
  93. Nicolosi A, Hauser WA, Musicco M, Kurland LT. Incidence and prognosis of brain abscess in a defined population: Olmsted County, Minnesota, 1935-1981. Neuroepidemiology 1991; 10: 122-31.
  94. Richards J, Sisson PR, Hickman JE, Ingham HR, Selkon JB. Microbiology, chemotherapy and mortality of brain abscess in Newcastle-upon-Tyne between 1979 and 1988. Scand J Infect Dis 1990; 22: 511-8.
  95. Svanteson B, Nordstrom CH, Rausing A. Non-traumatic brain abscess. Epidemiology, clinical symptoms and therapeutic results. Acta Neurochir (Wien ) 1988; 94: 57-65.
  96. Danziger A, Price H, Schechter MM. An analysis of 113 intracranial infections. Neuroradiology 1980; 19: 31-4.
  97. Hilmani S, Riyahi S, Ibahioin K, Naja A, El KA, El AA. [Brain abscess (80 cases)]. Neurochirurgie 2009; 55: 40-4.
  98. Morgan H, Wood MW, Murphey F. Experience with 88 consecutive cases of brain abscess. J Neurosurg 1973; 38: 698-704.
  99. Carey ME, Chou SN, French LA. Long-term neurological residua in patients surviving brain abscess with surgery. J Neurosurg 1971; 34: 652-6.
  100. Rish BL, Caveness WF, Dillon JD, Kistler JP, Mohr JP, Weiss GH. Analysis of brain abscess after penetrating craniocerebral injuries in Vietnam. Neurosurgery 1981; 9: 535-41.
  101. Gruszkiewicz J, Doron Y, Peyser E, Borovich B, Schachter J, Front D. Brain abscess and its surgical management. Surg Neurol 1982; 18: 7-17.
  102. Bradley PJ, Manning KP, Shaw MD. Brain abscess secondary to otitis media. J Laryngol Otol 1984; 98: 1185-91.
  103. Ersahin Y, Mutluer S, Guzelbag E. Brain abscess in infants and children. Childs Nerv Syst 1994; 10: 1859.
  104. Schliamser SE, Backman K, Norrby SR. Intracranial abscesses in adults: an analysis of 54 consecutive cases. Scand J Infect Dis 1988; 20: 1-9.
  105. Mathisen GE, Meyer RD, George WL, Citron DM, Finegold SM. Brain abscess and cerebritis. Rev Infect Dis 1984; 6 Suppl 1: S101-S106.
  106. Shaw MD, Russell JA. Cerebellar abscess. A review of 47 cases. J Neurol Neurosurg Psychiatry 1975; 38: 429-35.
  107. Nielsen H. Cerebral abscess in children. Neuropediatrics 1983; 14: 76-80.
  108. Hirsch JF, Roux FX, Sainte-Rose C, Renier D, Pierre-Kahn A. Brain abscess in childhood. A study of 34 cases treated by puncture and antibiotics. Childs Brain 1983; 10: 251-65.
  109. Moss SD, McLone DG, Arditi M, Yogev R. Pediatric cerebral abscess. Pediatr Neurosci 1988; 14: 291-6.
  110. Fischer EG, McLennan JE, Suzuki Y. Cerebral abscess in children. Am J Dis Child 1981; 135: 746-9.
  111. Dohrmann PJ, Elrick WL. Observations on brain abscess. Review of 28 cases. Med J Aust 1982; 2: 81-3.
  112. Sharma R, Mohandas K, Cooke RP. Intracranial abscesses: changes in epidemiology and management over five decades in Merseyside. Infection 2009; 37: 39-43.
  113. van Alphen HA, Dreissen JJ. Brain abscess and subdural empyema. Factors influencing mortality and results of various surgical techniques. J Neurol Neurosurg Psychiatry 1976; 39: 481-90.
  114. Al MM, Armougom F, Scheld WM et al. The expansion of the microbiological spectrum of brain abscesses with use of multiple 16S ribosomal DNA sequencing. Clin Infect Dis 2009; 48: 1169-78.
  115. de LJ, Gortvai P, Hurley R. Antibiotic treatment of abscesses of the central nervous system. Br Med J 1977; 2: 985-7.
  116. Mayhall CG, Archer NH, Lamb VA et al. Ventriculostomy-related infections. A prospective epidemiologic study. N Engl J Med 1984; 310: 553-9.
  117. Stenager E, Gerner-Smidt P, Kock-Jensen C. Ventriculostomy-related infections--an epidemiological study. Acta Neurochir (Wien ) 1986; 83: 20-3.
  118. Ohrstrom JK, Skou JK, Ejlertsen T, Kosteljanetz M. Infected ventriculostomy: bacteriology and treatment. Acta Neurochir (Wien ) 1989; 100: 67-9.
  119. Coplin WM, Avellino AM, Kim DK, Winn HR, Grady MS. Bacterial meningitis associated with lumbar drains: a retrospective cohort study. J Neurol Neurosurg Psychiatry 1999; 67: 468-73.
  120. Lyke KE, Obasanjo OO, Williams MA, O'Brien M, Chotani R, Perl TM. Ventriculitis complicating use of intraventricular catheters in adult neurosurgical patients. Clin Infect Dis 2001; 33: 2028-33.
  121. Wong GK, Poon WS, Wai S, Yu LM, Lyon D, Lam JM. Failure of regular external ventricular drain exchange to reduce cerebrospinal fluid infection: result of a randomised controlled trial. J Neurol Neurosurg Psychiatry 2002; 73: 759-61.
  122. Pfisterer W, Muhlbauer M, Czech T, Reinprecht A. Early diagnosis of external ventricular drainage infection: results of a prospective study. J Neurol Neurosurg Psychiatry 2003; 74: 929-32.
  123. Park P, Garton HJ, Kocan MJ, Thompson BG. Risk of infection with prolonged ventricular catheterization. Neurosurgery 2004; 55: 594-9.
  124. Arabi Y, Memish ZA, Balkhy HH et al. Ventriculostomy-associated infections: incidence and risk factors. Am J Infect Control 2005; 33: 137-43.
  125. Leverstein-van Hall MA, Hopmans TE, van der Sprenkel JW et al. A bundle approach to reduce the incidence of external ventricular and lumbar drain-related infections. J Neurosurg 2010; 112: 345-53.
  126. Schade RP, Schinkel J, Visser LG, Van Dijk JM, Voormolen JH, Kuijper EJ. Bacterial meningitis caused by the use of ventricular or lumbar cerebrospinal fluid catheters. J Neurosurg 2005; 102: 229-34.
  127. Walters BC, Hoffman HJ, Hendrick EB, Humphreys RP. Cerebrospinal fluid shunt infection. Influences on initial management and subsequent outcome. J Neurosurg 1984; 60: 1014-21.
  128. Filka J, Huttova M, Tuharsky J, Sagat T, Kralinsky K, Krcmery V, Jr. Nosocomial meningitis in children after ventriculoperitoneal shunt insertion. Acta Paediatr 1999; 88: 576-8.
  129. Kestle JR, Garton HJ, Whitehead WE et al. Management of shunt infections: a multicenter pilot study. J Neurosurg 2006; 105: 177-81.
  130. Sacar S, Turgut H, Toprak S et al. A retrospective study of central nervous system shunt infections diagnosed in a university hospital during a 4-year period. BMC Infect Dis 2006; 6:43.: 43.
  131. Aucoin PJ, Kotilainen HR, Gantz NM, Davidson R, Kellogg P, Stone B. Intracranial pressure monitors. Epidemiologic study of risk factors and infections. Am J Med 1986; 80: 369-76.
  132. Kourbeti IS, Jacobs AV, Koslow M, Karabetsos D, Holzman RS. Risk factors associated with postcraniotomy meningitis. Neurosurgery 2007; 60: 317-25.
  133. Federico G, Tumbarello M, Spanu T et al. Risk factors and prognostic indicators of bacterial meningitis in a cohort of 3580 postneurosurgical patients. Scand J Infect Dis 2001; 33: 533-7.
  134. Wang KW, Chang WN, Huang CR et al. Post-neurosurgical nosocomial bacterial meningitis in adults: microbiology, clinical features, and outcomes. J Clin Neurosci 2005; 12: 647-50.
  135. Zarrouk V, Vassor I, Bert F et al. Evaluation of the management of postoperative aseptic meningitis. Clin Infect Dis 2007; 44: 1555-9.
Volgende:
Gemeenschap verworven bacteriële meningitis