Kennislacunes

There is a large knowledge gap regarding the optimal treatment for acute hypersensitivity reactions to contrast media in children. An extensive search was performed but no papers were found that met the inclusion criteria. Therefore, a knowledge gap exists on this topic and better studies are needed to address this topic with the following research question:

 

What are the effects of different treatments to reduce symptoms of hypersensitivity reactions in children (<18 years of age) undergoing radiological examinations with contrast agents?

 

P(atients): Children (<18 years) with acute hypersensitivity reaction after administration of contrast media;

I(ntervention): Treatment, antihistamines, corticosteroids, epinephrine, adrenalin, dopamine, norepinephrine, noradrenalin, histamine H1 antagonists, histamine H2 antagonists, H1 antihistamines, H2 antihistamines, adrenergic beta-2 receptor agonists, glucocorticoids, management/treatment of hypersensitivity reactions/allergic reactions after contrast media, antihistamines, volume resuscitation, bronchodilators;

C(ontrol): Conservative treatment or comparison of interventions mentioned above;

O(utcome): Curation of acute allergic reactions, severity of complaints, morbidity, mortality, costs, hospitalization in an IC-unit, length of stay.