Kennislacunes

Module	Zoekvraag, PICO	Opmerkingen
Eiwitten bij nierinsufficiëntie	What are the (un)favorable effects of a protein enrichment compared to a standard amount of protein in the diet of ICU-patients with renal insufficiency without renal replacement therapy on mortality, length of stay (and other outcomes as defined in the PICO)?	More research is required to determine the optimal protein dose in critically ill patients with renal insufficiency. Especially in subgroups of critically ill patients (eg, those with burns, trauma, obesity, or recovering from surgery) that could benefit from higher doses of protein requires more research to define the optimal dose and timing of administration. Furthermore, it remains unknown whether a higher protein dose improves the physical recovery of survivors of critical illness, especially when protein is administered with exercise. Future trials evaluating higher protein dose starting later during the ICU stay, when patients are more likely to be anabolic, are warranted.

Module

Zoekvraag, PICO

Opmerkingen

Eiwitten bij nierinsufficiëntie

What are the (un)favorable effects of a protein enrichment compared to a standard amount of protein in the diet of ICU-patients with renal insufficiency without renal replacement therapy on mortality, length of stay (and other outcomes as defined in the PICO)?

More research is required to determine the optimal protein dose in critically ill patients with renal insufficiency. Especially in subgroups of critically ill patients (eg, those with burns, trauma, obesity, or recovering from surgery) that could benefit from higher doses of protein requires more research to define the optimal dose and timing of administration.

Furthermore, it remains unknown whether a higher protein dose improves the physical recovery of survivors of critical illness, especially when protein is administered with exercise. Future trials evaluating higher protein dose starting later during the ICU stay, when patients are more likely to be anabolic, are warranted.