Data-extractieformulier

General information

First author

Year

Intervention

comparison

Sponsorship

Study characteristic

Number (n) randomized per group

Study duration [w]

Concurrent treatment

Washout phase

Inclusion criteria

Minimal PASI

Age

Previous treatment required?

Baseline characteristics

Age [mean/median (range/SD)]

PASI [mean (SD/range)

DLQI [mean (SD/range)]

Female [%]

Weight [kg (SD, range)]

Withdrawals

Number of withdrawals with > = 1 dose

Due to AE in induction therapy

Due to AE in long-term therapy

Cochrane risk of bias

Sequence generation

Allocation concealment

Comment: allocation concealment

Comment: blinding of patients

Blinding of personnel and outcome

Incomplete outcome data

Selective outcome reporting

Other sources of bias

Intention to treat analysis

Results

induction: PASI response

Time of assessment [w]

PASI 75

PASI 90

induction: mean PASI

Time of assessment [w]

N

Mean PASI [±SD]

Mean PASI reduction from BL [±SD]

induction: PGA

Time of assessment [w]

Clear (PGA 0, PASI 100)

Clear/almost clear (PGA 0/1)

induction: DLQI

Time of assessment [w]

N

DLQI ≤5

Mean DLQI [±SD]

Mean reduction in DLQI [±SD]

Time until onset of action

TOA 25 PASI 75 [w]

TOA 25% mean PASI [w]

long-term: PASI response

Time of assessment [w]

PASI 75

PASI 90

Time of assessment [w]

PASI 75

PASI 90

long-term: mean PASI

Time of assessment [w]

N

Mean PASI [±SD]

Mean PASI reduction from BL [±SD]

long-term: PGA

Time of assessment [w]

Clear (PGA 0, PASI 100)

Clear/almost clear (PGA 0/1)

long-term: DLQI

Time of assessment [w]

N

DLQI ≤5

mean DLQI [±SD]

Mean reduction in DLQI [±SD]

Relapse

Median time to relapse (w)

Relapse rate at time x

AE induction

Time of assessment [w]

Number of patients with at least 1 AE

AE long-term

Time of assessment [w]

Number of patients with at least 1 AE

SAE induction

Time of assessment [w]

Number of patients with at least 1 SAE

SAE long-term

Time of assessment [w]

Number of patients with at least 1 SAE

Comments