1.    Key question

Wat is het effect van ondersteuning / adviezen / (verpleegkundige )interventies gericht op arbeid bij (A) tijdens of (B) na afloop van de in opzet curatieve behandeling van kanker op deelname aan het arbeidsproces, kwaliteit van leven, zinvolle dagbesteding , vermoeidheid, cognitief functioneren?

P: patiënten met kanker (A) tijdens of (B) na afloop van de in opzet curatieve behandeling van kanker (radiotherapie, chemotherapie, immunotherapie)

I: ondersteuning / adviezen / (verpleegkundige )interventies gericht op arbeid/terugkeer naar werk

C: reguliere zorg

O: deelname aan het arbeidsproces, kwaliteit van leven, zinvolle dagbesteding , vermoeidheid, cognitief functioneren, maatschappelijke participatie

2.    Search strategy

Search date: February 20, 2014.

Databases: OVID Medline, Embase and the Cochrane Library (see appendix for search strings).

Search limits:

• Publication date: 2008-2014;
• English and Dutch only;

-          Study design: meta-analyses, systematic reviews, RCTs.

3.    Search Results

Table 3. Overall search results.

a.   Excluded studies

1233 unique hits were screened on title and abstract (Table 3). Of these, 1605 were excluded. The most important reasons for exclusion were:

1. Other population: patients without cancers
2. Other intervention: interventions other than those specified
3. Wrong study design: narrative reviews, observational studies

Of the remaining 40 papers, the full-text was retrieved. Based on the full-text, an additional 33 studies were excluded. Table 4 provides an overview of these excluded studies.

b.    Included studies

The following 3 systematic reviews were included:

• de Boer AG, Taskila T, Tamminga SJ, Frings-Dresen MH, Feuerstein M, Verbeek JH. Interventions to enhance return-to-work for cancer patients. Cochrane Database of Systematic Reviews. 2011;2(2):CD007569.
• Egan MY, McEwen S, Sikora L, Chasen M, Fitch M, Eldred S. Rehabilitation following cancer treatment. Disability & Rehabilitation. 2013;35(26):2245-58.

-          Tamminga SJ, de Boer AGEM, Verbeek JHAM, Frings-Dresen MHW. Return-to-work interventions integrated into cancer care: a systematic review. Occup Environ Med. 2010;67(9):639-48.

The following 4 primary studies were included:

• Bjorneklett HG, Rosenblad A, Lindemalm C, Ojutkangas M-L, Letocha H, Strang P, et al. A randomized controlled trial of support group intervention after breast cancer treatment: results on sick leave, health care utilization and health economy. Acta Oncol. 2013;52(1):38-47.
• Hubbard G, Gray NM, Ayansina D, Evans JMM, Kyle RG. Case management vocational rehabilitation for women with breast cancer after surgery: a feasibility study incorporating a pilot randomised controlled trial. Trials [Electronic Resource]. 2013;14(175).
• Sherman DW, Haber J, Hoskins CN, Budin WC, Maislin G, Shukla S, et al. The effects of psychoeducation and telephone counseling on the adjustment of women with early-stage breast cancer. Applied Nursing Research. 2012;25(1):3-16.

-          Tamminga SJ, Verbeek JHAM, Bos MMEM, Fons G, Kitzen JJEM, Plaisier PW, et al. Effectiveness of a hospital-based work support intervention for female cancer patients - a multi-centre randomised controlled trial. PLoS ONE [Electronic Resource]. 2013;8(5):e63271.

Table 4. Key question 2: overview of excluded studies based on full-text evaluation.

Search strings Question 1

1.    medline (ovid)

1     exp "Patient Acceptance of Health Care"/ (159633)

2     Patient Dropouts/ (6469)

3     complian*.ti,ab. (79272)

4     comply*.ti,ab. (7923)

5     complied.ti,ab. (2692)

6     adher*.ti,ab. (106198)

7     noncomplian*.ti,ab. (5802)

8     nonadher*.ti,ab. (5840)

9     uptake.ti,ab. (235728)

10     (patient adj dropout*).ti,ab. (144)

11     (treatment* adj refusal*).ti,ab. (219)

12     (patient adj participation).ti,ab. (1153)

13     (patient adj acceptance).ti,ab. (2050)

14     maintenance.ti,ab. (172295)

15     variance*.ti,ab. (103492)

16     or/1-15 (821663)

17     Attitude to Health/ or Attitude/ or attitude.ti,ab. (130855)

18     motivation/ or "aspirations (psychology)"/ or drive/ or exploratory behavior/ or goals/ or intention/ or exp personality/ (272618)

19     personality.ti,ab. (49492)

20     behavio?r.ti,ab. (452604)

21     "Social Determinants of Health"/ (46)

22     determinant*.ti,ab. (151108)

23     risk factors/ (543003)

24     exp Socioeconomic Factors/ (329278)

25     predictor*.ti,ab. (187802)

26     social support/ (49664)

27     or/17-26 (1829337)

28    exercise/ or physical conditioning, human/ or resistance training/ or exp running/ or swimming/ or walking/ or exp physical endurance/ or physical fitness/ (133314)

29     exercise movement techniques/ or exercise therapy/ (25219)

30     Movement/ (57861)

31     exp Sports/ (123692)

32     exp "Physical Education and Training"/ (13241)

33     (physical$ adj (active or activity or activities)).ti,ab. (51727)

34     ((MUSCLE or MUSCLES) adj STRENGTHEN$).ti,ab. (461)

35     (SWIM$ or JOG$ or RUN or RUNNING or WALK or WALKING).ti,ab. (154990)

36     ((CIRCUIT$ or RESISTANCE or STRENGTH$ or PHYSICAL or WEIGHT) adj (TRAIN or TRAINING)).ti,ab. (9920)

37     exercise$.ti,ab. (178609)

38     (sport or sports).ti,ab. (33684)

39     aerobic$.ti,ab. (51281)

40     Diet/ or Diet Therapy/ (114787)

41     Nutrition Policy/ or Nutrition Therapy/ (6735)

42     Food Habits/ (20015)

43     (diet or diets or dieta* or diete* or dieti* or nutrition* or food habit* or feeding behavio?r* or eating behavio?r*).ti,ab. (441506)

44    exp Smoking/dt, pc, th [Drug Therapy, Prevention & Control, Therapy] (16352)

45     exp "Tobacco Use Cessation"/ (19909)

46     "Tobacco Use"/pc [Prevention & Control] (5)

47     smoking cessation.ti,ab. (14028)

48     alcohol*.ti,ab. (209186)

49     (binge or drink*).ti,ab. (90807)

50     alcoholism.ti,ab. (23460)

51     exp Drinking Behavior/ (55217)

52     alcohol-related disorders/ or alcoholic intoxication/ or binge drinking/ (13959)

53     exp Body Weight/ (337807)

54     (body adj (weight or mass)).ti,ab. (231700)

55     exp Body Mass Index/ (75735)

56     (body mass index or bmi).ti,ab. (112728)

57     or/28-56 (1607477)

58     exp Neoplasms/ (2500226)

59     Neoplasm Staging/ (117868)

60     cancer$.ti,ab. (977619)

61     tumor$.ti,ab. (894871)

62     tumour$.ti,ab. (191122)

63     carcinoma$.ti,ab. (440172)

64     neoplasm$.ti,ab. (91896)

65     lymphoma.ti,ab. (105058)

66     melanoma.ti,ab. (71051)

67     staging.ti,ab. (47126)

68     metastas$.ti,ab. (204235)

69     metastatic.ti,ab. (130906)

70     exp Neoplasm Metastasis/ (152159)

71     exp neoplastic processes/ (324767)

72     neoplastic process$.ti,ab. (2232)

73     non small cell.ti,ab. (28473)

74     adenocarcinoma$.ti,ab. (89573)

75     squamous cell.ti,ab. (61763)

76     nsclc.ti,ab. (16326)

77     osteosarcoma$.ti,ab. (14066)

78     phyllodes.ti,ab. (1236)

79     cystosarcoma$.ti,ab. (550)

80     fibroadenoma$.ti,ab. (2852)

81     (non adj small adj cell).ti,ab. (28473)

82     (non adj2 small adj2 cell).ti,ab. (28676)

83     (nonsmall adj2 cell).ti,ab. (1675)

84     plasmacytoma$.ti,ab. (5100)

85     myeloma.ti,ab. (34460)

86     multiple myeloma.ti,ab. (22219)

87     lymphoblastoma$.ti,ab. (258)

88     lymphocytoma$.ti,ab. (262)

89     lymphosarcoma$.ti,ab. (3589)

90     immunocytoma.ti,ab. (401)

91     sarcoma$.ti,ab. (68681)

92     hodgkin$.ti,ab. (49979)

93     (nonhodgkin$ or non hodgkin$).ti,ab. (28698)

94     or/58-93 (2879101)

95     16 and 27 and 57 and 94 (1646)

96     limit 95 to yr="2008 - 2014" (740)

2.    PreMedline (OVID)

97    complian*.ti,ab. (5839)

98     comply*.ti,ab. (653)

99     complied.ti,ab. (193)

100     adher*.ti,ab. (8530)

101     noncomplian*.ti,ab. (350)

102     nonadher*.ti,ab. (399)

103     uptake.ti,ab. (15519)

104     (patient adj dropout*).ti,ab. (7)

105   (treatment* adj refusal*).ti,ab. (10)

106     (patient adj participation).ti,ab. (100)

107     (patient adj acceptance).ti,ab. (112)

108     maintenance.ti,ab. (11790)

109     variance*.ti,ab. (10666)

110     or/97-109 (51895)

111     attitude.ti,ab. (2386)

112     (motivation or aspiration* or drive or goal* or intention*).ti,ab. (32896)

113     personality.ti,ab. (3335)

114     behavio?r.ti,ab. (68045)

115     determinant*.ti,ab. (8752)

116     risk factor*.ti,ab. (25613)

117     socioeconomic.ti,ab. (3559)

118     predictor*.ti,ab. (16066)

119     social support.ti,ab. (1603)

120     or/111-119 (148731)

121     (physical$ adj (active or activity or activities)).ti,ab. (5548)

122     ((MUSCLE or MUSCLES) adj STRENGTHEN$).ti,ab. (66)

123     (SWIM$ or JOG$ or RUN or RUNNING or WALK or WALKING).ti,ab. (15925)

124     ((CIRCUIT$ or RESISTANCE or STRENGTH$ or PHYSICAL or WEIGHT) adj (TRAIN or TRAINING)).ti,ab. (901)

125     exercise$.ti,ab. (12803)

126     (sport or sports).ti,ab. (4194)

127     aerobic$.ti,ab. (4763)

128     (diet or diets or dieta* or diete* or dieti* or nutrition* or food habit* or feeding behavio?r* or eating behavio?r*).ti,ab. (31337)

129     smoking cessation.ti,ab. (1127)

130     alcohol*.ti,ab. (18816)

131     (binge or drink*).ti,ab. (6138)

132     alcoholism.ti,ab. (917)

133     (body adj (weight or mass)).ti,ab. (16899)

134     (body mass index or bmi).ti,ab. (11875)

135     or/121-134 (99865)

136     neoplasm*.ti,ab. (5465)

137     cancer$.ti,ab. (73743)

138     tumor$.ti,ab. (53329)

139     tumour$.ti,ab. (11056)

140     carcinoma$.ti,ab. (24735)

141     neoplasm$.ti,ab. (5465)

142     lymphoma.ti,ab. (5446)

143     melanoma.ti,ab. (3660)

144     staging.ti,ab. (3178)

145     metastas$.ti,ab. (14682)

146     metastatic.ti,ab. (9555)

147     neoplastic process$.ti,ab. (109)

148     non small cell.ti,ab. (3096)

149     adenocarcinoma$.ti,ab. (5660)

150     squamous cell.ti,ab. (4340)

151     nsclc.ti,ab. (2195)

152     osteosarcoma$.ti,ab. (873)

153     phyllodes.ti,ab. (86)

154    cystosarcoma$.ti,ab. (15)

155     fibroadenoma$.ti,ab. (151)

156     (non adj small adj cell).ti,ab. (3096)

157     (non adj2 small adj2 cell).ti,ab. (3102)

158     (nonsmall adj2 cell).ti,ab. (162)

159     plasmacytoma$.ti,ab. (182)

160     myeloma.ti,ab. (1734)

161     multiple myeloma.ti,ab. (1390)

162     lymphoblastoma$.ti,ab. (12)

163     lymphocytoma$.ti,ab. (12)

164     lymphosarcoma$.ti,ab. (89)

165     immunocytoma.ti,ab. (2)

166     sarcoma$.ti,ab. (4038)

167     hodgkin$.ti,ab. (1975)

168    (nonhodgkin$ or non hodgkin$).ti,ab. (1268)

169     or/136-168 (130134)

170     110 and 120 and 135 and 169 (107)

171     limit 170 to yr="2008 - 2014" (93)

3.    EMBASE (via embase.com)

4.    cochrane library (via wiley)

#1            MeSH descriptor: [Patient Acceptance of Health Care] 1 tree(s) exploded

#2            MeSH descriptor: [Patient Dropouts] 1 tree(s) exploded

#3            (complian* or comply* or complied or adher* or noncomplian* or nonadher* or uptake or (patient and dropout*) or (treatment and refusal*) or (patient and (participation or acceptance)) or maintenance):ti,ab

#4            #1 or #2 or #3

#5            MeSH descriptor: [Attitude to Health] 1 tree(s) exploded

#6            MeSH descriptor: [Attitude] this term only

#7            MeSH descriptor: [Motivation] this term only

#8            MeSH descriptor: [Aspirations (Psychology)] this term only

#9            MeSH descriptor: [Drive] this term only

#10          MeSH descriptor: [Exploratory Behavior] this term only

#11          MeSH descriptor: [Goals] this term only

#12          MeSH descriptor: [Intention] this term only

#13          MeSH descriptor: [Personality] 1 tree(s) exploded

#14          MeSH descriptor: [Social Determinants of Health] this term only

#15          MeSH descriptor: [Risk Factors] this term only

#16          MeSH descriptor: [Socioeconomic Factors] explode all trees

#17          MeSH descriptor: [Social Support] this term only

#18          (attitude or personality or behavior or behaviour or determinant or predictor):ab,ti

#19          #5 or #6 or #7 or #8 or #9 or #10 or #11 or #12 or #13 or #14 or #15 or #16 or #17 or #18

#20          MeSH descriptor: [Exercise] this term only

#21          MeSH descriptor: [Physical Conditioning, Human] this term only

#22          MeSH descriptor: [Resistance Training] this term only

#23          MeSH descriptor: [Sports] 1 tree(s) exploded

#24          MeSH descriptor: [Physical Endurance] 1 tree(s) exploded

#25          MeSH descriptor: [Physical Fitness] this term only

#26          MeSH descriptor: [Exercise Movement Techniques] this term only

#27          MeSH descriptor: [Exercise Therapy] this term only

#28          MeSH descriptor: [Movement] this term only

#29          MeSH descriptor: [Physical Education and Training] 1 tree(s) exploded

#30          ((physical* and (active or activity or activities)) or ((muscle or muscles) and strengthen*) or swim* or jog* or run or running or walk or walking or exercise* or sport or sports or aerobic):ab,ti

#31          MeSH descriptor: [Diet] this term only

#32          MeSH descriptor: [Diet Therapy] this term only

#33          MeSH descriptor: [Nutrition Policy] this term only

#34          MeSH descriptor: [Nutrition Therapy] this term only

#35          MeSH descriptor: [Food Habits] this term only

#36          (diet or diets or dieta* or diete* or dieti* or nutrition* or food habit* or (feeding and (behavior* or behaviour*)) or (eating and (behavior* or behaviour*))):ti,ab

#37          MeSH descriptor: [Tobacco Use Cessation] 1 tree(s) exploded

#38          MeSH descriptor: [Tobacco Use] this term only

#39          (smoking and cessation):ti,ab

#40          MeSH descriptor: [Drinking Behavior] 1 tree(s) exploded

#41          MeSH descriptor: [Alcohol-Related Disorders] this term only

#42          MeSH descriptor: [Binge Drinking] this term only

#43          MeSH descriptor: [Alcoholic Intoxication] this term only

#44          (alcohol* or binge or drink*):ti,ab

#45          MeSH descriptor: [Body Weight] 1 tree(s) exploded

#46          MeSH descriptor: [Body Mass Index] 1 tree(s) exploded

#47          ((body and (weight or mass)) or bmi):ti,ab

#48          #20 or #21 or #22 or #23 or #24 or #25 or #26 or #27 or #28 or #29 or #30 or #31 or #32 or #33 or #34 or #35 or #36 or #37 or #38 or #39 or #40 or #41 or #42 or #43 or #44 or #45 or #46 or #47

#49          MeSH descriptor: [Neoplasms] 1 tree(s) exploded

#50          MeSH descriptor: [Neoplasm Staging] this term only

#51          MeSH descriptor: [Neoplasm Metastasis] 1 tree(s) exploded

#52          MeSH descriptor: [Neoplastic Processes] 1 tree(s) exploded

#53          (cancer* or tumor* or tumour* or carcinoma* or neoplasm* or lymphoma or melanoma or metastas* or metastatic or (non and small and cell) or adenocarcinoma* or (squamous and cell) or nsclc or osteosarcoma* or phyllodes or cystosarcoma* or fibroadenoma* or plasmacytoma* or myeloma* or lymphoblastoma* or lymphocytoma* or sarcoma* or hodgkin* or nonhodgkin*):ti,ab

#54          #49 or #50 or #51 or #52 or #53

#55          #4 and #19 and #48 and #54

5.    CINAHL

6.    PEDRO

Subdiscipline oncology: Abstract & Title

• complian*: N=15
• comply: N=5
• complied: N=0
• adher*: N=86
• noncomplian*: N=1
• nonadher*: N=0
• uptake: N=14
• dropout: N=8
• refusal: N=2
• acceptance: N=6
• maintenance: N=32

Search strings Question 2

1.    medline (ovid)

1     exp Neoplasms/ (2498041)

2     Neoplasm Staging/ (117705)

3     cancer$.ti,ab. (976234)

4     tumor$.ti,ab. (893907)

5     tumour$.ti,ab. (190963)

6     carcinoma$.ti,ab. (439770)

7     neoplasm$.ti,ab. (91812)

8     lymphoma.ti,ab. (104945)

9     melanoma.ti,ab. (70977)

10     staging.ti,ab. (47081)

11     metastas$.ti,ab. (203996)

12     metastatic.ti,ab. (130750)

13     exp Neoplasm Metastasis/ (152011)

14     exp neoplastic processes/ (324415)

15     neoplastic process$.ti,ab. (2230)

16     non small cell.ti,ab. (28431)

17     adenocarcinoma$.ti,ab. (89494)

18     squamous cell.ti,ab. (61682)

19     nsclc.ti,ab. (16298)

20     osteosarcoma$.ti,ab. (14053)

21     phyllodes.ti,ab. (1234)

22     cystosarcoma$.ti,ab. (550)

23     fibroadenoma$.ti,ab. (2852)

24     (non adj small adj cell).ti,ab. (28431)

25     (non adj2 small adj2 cell).ti,ab. (28634)

26     (nonsmall adj2 cell).ti,ab. (1673)

27     plasmacytoma$.ti,ab. (5097)

28     myeloma.ti,ab. (34422)

29     multiple myeloma.ti,ab. (22186)

30     lymphoblastoma$.ti,ab. (258)

31     lymphocytoma$.ti,ab. (261)

32     lymphosarcoma$.ti,ab. (3588)

33     immunocytoma.ti,ab. (401)

34     sarcoma$.ti,ab. (68644)

35     hodgkin$.ti,ab. (49942)

36     (nonhodgkin$ or non hodgkin$).ti,ab. (28671)

37     or/1-36 (2876408)

38     return-to-work.tw. (5270)

39     employment.tw. (33619)

40     unemployment.tw. (6136)

41     unemployed.tw. (4795)

42     retirement.tw. (7735)

43     sick leave.tw. (2995)

44     sickness absence.tw. (1349)

45     absenteeism.tw. (3414)

46     disability management.tw. (194)

47     exp Employment/ (53009)

48     exp Unemployment/ (5058)

49     exp Sick Leave/ (3747)

50     exp Absenteeism/ (7153)

51     exp Work/ (13295)

52     exp Occupations/ (26182)

53     exp Occupational Medicine/ (21660)

54     exp Occupational Health/ (24383)

55     exp Occupational Health Services/ (9554)

56     exp Rehabilitation, Vocational/ (8955)

57     occupation*.tw. (103213)

58     vocational*.tw. (7487)

59     work ability.tw. (680)

60     work capacity.tw. (3783)

61     work activity.tw. (520)

62     work disability.tw. (1257)

63     work rehabilitation.tw. (180)

64     work status.tw. (1175)

65     work retention.tw. (36)

66     workability.tw. (180)

67     employability.tw. (361)

68     employable.tw. (166)

69     employee*.tw. (29493)

70     or/38-69 (282110)

71     37 and 70 (19125)

72    randomized controlled trial.pt. (362054)

73     controlled clinical trial.pt. (87462)

74     randomized.ab. (262574)

75     placebo.ab. (142174)

76     clinical trials as topic.sh. (167631)

77     randomly.ab. (187448)

78     trial.ti. (112531)

79     72 or 73 or 74 or 75 or 76 or 77 or 78 (833512)

80     exp animals/ not humans.sh. (3878559)

81     79 not 80 (765630)

82     meta-analysis.mp,pt. or review.pt. or search:.tw. (1985170)

83     81 or 82 (2634437)

84     71 and 83 (3829)

85     limit 84 to yr="2008 - 2014" (937)

2.    PreMedline (OVID)

3     cancer$.ti,ab. (73823)

4     tumor$.ti,ab. (53379)

5     tumour$.ti,ab. (11030)

6     carcinoma$.ti,ab. (24756)

7     neoplasm$.ti,ab. (5448)

8     lymphoma.ti,ab. (5414)

9     melanoma.ti,ab. (3665)

10     staging.ti,ab. (3159)

11     metastas$.ti,ab. (14702)

12     metastatic.ti,ab. (9582)

15     neoplastic process$.ti,ab. (110)

16     non small cell.ti,ab. (3082)

17     adenocarcinoma$.ti,ab. (5663)

18     squamous cell.ti,ab. (4332)

19     nsclc.ti,ab. (2180)

20     osteosarcoma$.ti,ab. (874)

21     phyllodes.ti,ab. (88)

22     cystosarcoma$.ti,ab. (15)

23     fibroadenoma$.ti,ab. (151)

24     (non adj small adj cell).ti,ab. (3082)

25     (non adj2 small adj2 cell).ti,ab. (3087)

26     (nonsmall adj2 cell).ti,ab. (162)

27     plasmacytoma$.ti,ab. (181)

28     myeloma.ti,ab. (1734)

29     multiple myeloma.ti,ab. (1388)

30     lymphoblastoma$.ti,ab. (12)

31     lymphocytoma$.ti,ab. (12)

32     lymphosarcoma$.ti,ab. (89)

33     immunocytoma.ti,ab. (2)

34     sarcoma$.ti,ab. (4044)

35     hodgkin$.ti,ab. (1968)

36     (nonhodgkin$ or non hodgkin$).ti,ab. (1264)

37     or/3-36 (130223)

38     return-to-work.tw. (422)

39     employment.tw. (2491)

40     unemployment.tw. (420)

41     unemployed.tw. (362)

42     retirement.tw. (498)

43     sick leave.tw. (207)

44     sickness absence.tw. (97)

45     absenteeism.tw. (233)

46     disability management.tw. (17)

57     occupation*.tw. (7192)

58     vocational*.tw. (486)

59     work ability.tw. (88)

60     work capacity.tw. (85)

61     work activity.tw. (36)

62     work disability.tw. (75)

63     work rehabilitation.tw. (18)

64     work status.tw. (110)

65     work retention.tw. (5)

66     workability.tw. (31)

67     employability.tw. (32)

68     employable.tw. (10)

69    employee*.tw. (1570)

70     or/38-69 (12739)

71     37 and 70 (718)

72     randomized controlled trial.pt. (608)

73     controlled clinical trial.pt. (68)

74     randomized.ab. (20396)

75     placebo.ab. (7553)

76     clinical trials as topic.sh. (1)

77    randomly.ab. (18269)

78     trial.ti. (8324)

79     72 or 73 or 74 or 75 or 76 or 77 or 78 (43809)

80     exp animals/ not humans.sh. (5)

81     79 not 80 (43809)

82     meta-analysis.mp,pt. or review.pt. or search:.tw. (30886)

83     81 or 82 (71201)

84     71 and 83 (64)

85     limit 84 to yr="2008 - 2014" (54)

3.    EMBASE (via embase.com)

4.    cochrane library (via wiley)

#1            (return-to-work or employment or unemployment or retirement or 'sick leave' or 'sickness absence' or absenteeism or 'disability management' or occupation* or vocational* or 'work ability' or 'work capacity' or 'work activity' or 'work disability' or 'work rehabilitation' or 'work status' or 'work retention' or workability or employability or employable or employee*):ab,ti

#2            MeSH descriptor: [Employment] 1 tree(s) exploded

#3            MeSH descriptor: [Sick Leave] 1 tree(s) exploded

#4            MeSH descriptor: [Absenteeism] explode all trees

#5            MeSH descriptor: [Work] 1 tree(s) exploded

#6            MeSH descriptor: [Occupations] 1 tree(s) exploded

#7            MeSH descriptor: [Occupational Medicine] 1 tree(s) exploded

#8            MeSH descriptor: [Occupational Health] 1 tree(s) exploded

#9            MeSH descriptor: [Occupational Health Services] 1 tree(s) exploded

#10          MeSH descriptor: [Rehabilitation, Vocational] 1 tree(s) exploded

#11          #1 or #2 or #3 or #4 or #5 or #6 or #7 or #8 or #9 or #10

#12          MeSH descriptor: [Neoplasms] 1 tree(s) exploded

#13          MeSH descriptor: [Neoplasm Staging] this term only

#14          MeSH descriptor: [Neoplasm Metastasis] 1 tree(s) exploded

#15          MeSH descriptor: [Neoplastic Processes] 1 tree(s) exploded

#16          (cancer* or tumor* or tumour* or carcinoma* or neoplasm* or lymphoma or melanoma or metastas* or metastatic or (non and small and cell) or adenocarcinoma* or (squamous and cell) or nsclc or osteosarcoma* or phyllodes or cystosarcoma* or fibroadenoma* or plasmacytoma* or myeloma* or lymphoblastoma* or lymphocytoma* or sarcoma* or hodgkin* or nonhodgkin*):ti,ab

#17          #12 or #13 or #14 or #15 or #16

#18          #11 and #17

5.    CINAHL

6.    PSYCINFO

1     exp Neoplasms/ (33378)

2     cancer$.ti,ab. (37451)

3     tumor$.ti,ab. (9112)

4     tumour$.ti,ab. (1283)

5     carcinoma$.ti,ab. (1192)

6     neoplasm$.ti,ab. (773)

7     lymphoma.ti,ab. (731)

8     melanoma.ti,ab. (526)

9     staging.ti,ab. (1395)

10     metastas$.ti,ab. (905)

11     metastatic.ti,ab. (1024)

12     neoplastic process$.ti,ab. (18)

13    non small cell.ti,ab. (149)

14     adenocarcinoma$.ti,ab. (205)

15     squamous cell.ti,ab. (145)

16     nsclc.ti,ab. (61)

17     osteosarcoma$.ti,ab. (57)

18     phyllodes.ti,ab. (0)

19     cystosarcoma$.ti,ab. (0)

20     fibroadenoma$.ti,ab. (2)

21    (non adj small adj cell).ti,ab. (149)

22     (non adj2 small adj2 cell).ti,ab. (151)

23     (nonsmall adj2 cell).ti,ab. (24)

24     plasmacytoma$.ti,ab. (8)

25     myeloma.ti,ab. (159)

26     lymphoblastoma$.ti,ab. (1)

27     lymphocytoma$.ti,ab. (0)

28     lymphosarcoma$.ti,ab. (7)

29     immunocytoma.ti,ab. (0)

30     sarcoma$.ti,ab. (301)

31     hodgkin$.ti,ab. (559)

32     (nonhodgkin$ or non hodgkin$).ti,ab. (184)

33     or/1-32 (51298)

34     return-to-work.tw. (1606)

35     employment.tw. (37030)

36     unemployment.tw. (6677)

37     unemployed.tw. (4879)

38     retirement.tw. (6934)

39     sick leave.tw. (869)

40     sickness absence.tw. (606)

41     absenteeism.tw. (3058)

42     disability management.tw. (198)

43     exp Employment Status/ (14085)

44     exp Unemployment/ (3103)

45     exp Employee Leave Benefits/ (651)

46     exp Employee Absenteeism/ or exp Employee Attitudes/ (27338)

47     exp "Work (Attitudes Toward)"/ (5430)

48     exp Occupations/ (7341)

49     exp Occupational Health/ (796)

50     exp Vocational Rehabilitation/ (5904)

51     occupation*.tw. (50380)

52     vocational*.tw. (30461)

53     work ability.tw. (585)

54     work capacity.tw. (430)

55     work activity.tw. (501)

56     work disability.tw. (360)

57     work rehabilitation.tw. (182)

58     work status.tw. (800)

59     work retention.tw. (15)

60     workability.tw. (71)

61     employability.tw. (1108)

62     employable.tw. (168)

63     employee*.tw. (46201)

64     or/34-63 (181694)

65     33 and 64 (1278)

66     limit 65 to yr="2008 - 2014" (632)

67     randomized.ab. (36974)

68     placebo.ab. (29643)

69     randomly.ab. (49634)

70     trial.ti. (16816)

71     exp clinical trials/ (7311)

72     meta-analysis.mp,pt. or review.pt. or search:.tw. (72511)

73     67 or 68 or 69 or 70 or 71 or 72 (179795)

74     66 and 73 (54)