Zoekverantwoording Arbeid

1. Key question

Wat is het effect van ondersteuning / adviezen / (verpleegkundige )interventies gericht op arbeid bij (A) tijdens of (B) na afloop van de in opzet curatieve behandeling van kanker op deelname aan het arbeidsproces, kwaliteit van leven, zinvolle dagbesteding , vermoeidheid, cognitief functioneren?

P: patiënten met kanker (A) tijdens of (B) na afloop van de in opzet curatieve behandeling van kanker (radiotherapie, chemotherapie, immunotherapie)

I: ondersteuning / adviezen / (verpleegkundige )interventies gericht op arbeid/terugkeer naar werk

C: reguliere zorg

O: deelname aan het arbeidsproces, kwaliteit van leven, zinvolle dagbesteding , vermoeidheid, cognitief functioneren, maatschappelijke participatie

2. Search strategy

Search date: February 20, 2014.

Databases: OVID Medline, Embase and the Cochrane Library (see appendix for search strings).

Search limits:

Publication date: 2008-2014;
English and Dutch only;

- Study design: meta-analyses, systematic reviews, RCTs.

3. Search Results

Table 3. Overall search results.

Database	Number of hits
OVID Medline	937
OVID PreMedline	54
EMBASE.com	352
Cochrane Database of Systematic Reviews	49
DARE	1
HTA database	2
CENTRAL	563
Cinahl	38
PsycInfo	54
Total hits	2050
N excluded (language, year, duplicates)	817
Total unique eligible hits	1233

a. Excluded studies

1233 unique hits were screened on title and abstract (Table 3). Of these, 1605 were excluded. The most important reasons for exclusion were:

Other population: patients without cancers
Other intervention: interventions other than those specified
Wrong study design: narrative reviews, observational studies

Of the remaining 40 papers, the full-text was retrieved. Based on the full-text, an additional 33 studies were excluded. Table 4 provides an overview of these excluded studies.

b. Included studies

The following 3 systematic reviews were included:

de Boer AG, Taskila T, Tamminga SJ, Frings-Dresen MH, Feuerstein M, Verbeek JH. Interventions to enhance return-to-work for cancer patients. Cochrane Database of Systematic Reviews. 2011;2(2):CD007569.
Egan MY, McEwen S, Sikora L, Chasen M, Fitch M, Eldred S. Rehabilitation following cancer treatment. Disability & Rehabilitation. 2013;35(26):2245-58.

- Tamminga SJ, de Boer AGEM, Verbeek JHAM, Frings-Dresen MHW. Return-to-work interventions integrated into cancer care: a systematic review. Occup Environ Med. 2010;67(9):639-48.

The following 4 primary studies were included:

Bjorneklett HG, Rosenblad A, Lindemalm C, Ojutkangas M-L, Letocha H, Strang P, et al. A randomized controlled trial of support group intervention after breast cancer treatment: results on sick leave, health care utilization and health economy. Acta Oncol. 2013;52(1):38-47.
Hubbard G, Gray NM, Ayansina D, Evans JMM, Kyle RG. Case management vocational rehabilitation for women with breast cancer after surgery: a feasibility study incorporating a pilot randomised controlled trial. Trials [Electronic Resource]. 2013;14(175).
Sherman DW, Haber J, Hoskins CN, Budin WC, Maislin G, Shukla S, et al. The effects of psychoeducation and telephone counseling on the adjustment of women with early-stage breast cancer. Applied Nursing Research. 2012;25(1):3-16.

- Tamminga SJ, Verbeek JHAM, Bos MMEM, Fons G, Kitzen JJEM, Plaisier PW, et al. Effectiveness of a hospital-based work support intervention for female cancer patients - a multi-centre randomised controlled trial. PLoS ONE [Electronic Resource]. 2013;8(5):e63271.

Table 4. Key question 2: overview of excluded studies based on full-text evaluation.

Author	Reference	Title	Reason
Amir Z	Occup Med (Oxf) 2009 59(6):373-7	Cancer survivorship and employment: epidemiology	Narrative review
Brocki BC	Lung Cancer 2014 83(1):102-8	Short and long-term effects of supervised versus unsupervised exercise training on health-related quality of life and functional outcomes following lung cancer surgery - A randomized controlled trial	Geen interventie gericht op arbeid
Buffart LM	Cancer Treat. Rev. 2014 40(2):327-340	Evidence-based physical activity guidelines for cancer survivors: Current guidelines, knowledge gaps and future research directions	Overzicht van EB guidelines over exercise
de Boer AGEM	Occup Med (Oxf) 2009 59(6):378-80	Employment and the common cancers: return to work of cancer survivors	Narrative review
de Boer AGEM	JAMA 2009 301(7):753-62	Cancer survivors and unemployment: a meta-analysis and meta-regression	Gaat over risico op werkloosheid
De Boer AGM	Cochrane Database Syst. Rev. 2009 1):	Interventions to enhance return-to-work for cancer patients	Updated door de Boer 2011
Duijts SFA	Psycho-Oncology 2013	Physical and psychosocial problems in cancer survivors beyond return to work: A systematic review	Review van psychosociale problemen na return to work
Farley Short P	JAMA 2009 302(1):33; author reply 34-5	Employment status among cancer survivors	Letter
Feuerstein M	J 2010 4(4):415-37	Work in cancer survivors: a model for practice and research	Geen review van interventies
Franco G	Med Lav 2013 104(2):87-92	Occupation and breast cancer: fitness for work is an aspect that needs to be addressed	Narrative review
Gudbergsson SB	Minerva Psichiatr. 2008 49(1):45-60	Aspects of the work situation of cancer survivors	Niet verkrijgbaar
Hegel MT	Psycho-Oncology 2011 20(10):1092-1101	Feasibility study of a randomized controlled trial of a telephone-delivered problem-solving-occupational therapy intervention to reduce participation restrictions in rural breast cancer survivors undergoing chemotherapy	Is eigenlijk een haalbaarheidsstudie
Horsboel TA	Eur J Cancer Care (Engl) 2012 21(4):424-35	Factors associated with work outcome for survivors from haematological malignancies--a systematic literature review	Geen review van interventies
Hoving JL	BMC Cancer 2009 9(117):	Return to work of breast cancer survivors: a systematic review of intervention studies	Geen kwaliteitsbeoordeling van geïncludeerde studies
Juvet LK	Database of Abstracts of Reviews of Effects 2009 1):1	Rehabilitation of breast cancer patients: systematic review (Provisional abstract)	Noors
Khan F	Cochrane Database of Systematic Reviews 2013 1):	Multidisciplinary rehabilitation after primary brain tumour treatment	Te specifiek
Kyle RG	Trials [Electronic Resource] 2011 12(89):	Vocational rehabilitation services for patients with cancer: design of a feasibility study incorporating a pilot randomised controlled trial among women with breast cancer following surgery	Design van Hubbard 2013
Mak AKY	Journal of Occupational Rehabilitation 2011 21(1):	Toward an occupational rehabilitation policy community for cancer survivors in Singapore: a stakeholder perspective from the SME employers	Narrative review
Martin TA	JBI Database Syst. Rev. Implement. Rep. 2013 11(9):258-309	Effectiveness of individualized survivorship care plans on quality of life of adult female breast cancer survivors: A systematic review	Geen interventie gericht op arbeid
Mehnert A	Crit Rev Oncol Hematol 2011 77(2):109-30	Employment and work-related issues in cancer survivors	Geen review van interventies
Mehnert A	Cancer 2013 11(2151-9	Employment challenges for cancer survivors	Narrative review
Munir F	Occup Med (Oxf) 2009 59(6):381-9	Employment and the common cancers: correlates of work ability during or following cancer treatment	Geen review van interventies
Silver JK	Am J Phys Med Rehabil 2011 90(5 Suppl 1):S5-15	Cancer rehabilitation with a focus on evidence-based outpatient physical and occupational therapy interventions	Narrative review
Silver JK	WORK 2013 46(4):455-72	Cancer rehabilitation may improve function in survivors and decrease the economic burden of cancer to individuals and society	Narrative review
Steiner JF	Psychooncology 2010 19(2):115-24	Returning to work after cancer: quantitative studies and prototypical narratives	Geen review van interventies
Stigt JA	J. Thorac. Oncol. 2013 8(2):214-221	A randomized controlled trial of postthoracotomy pulmonary rehabilitation in patients with resectable lung cancer	Geen interventie gericht op arbeid
Tamminga SJ	J Occup Rehabil 2012 22(4):565-78	A hospital-based work support intervention to enhance the return to work of cancer patients: a process evaluation	Evaluatie van 1 arm van een RCT
Tamminga SJ	BMC Cancer 2010 10(345):	Enhancing return-to-work in cancer patients, development of an intervention and design of a randomised controlled trial	Studie protocol
Tiedtke C	Psychooncology 2010 19(7):677-83	Experiences and concerns about 'returning to work' for women breast cancer survivors: a literature review	Niet over interventies, maar over ervaringen
van Dalen EC	JAMA 2009 302(1):33-4; author reply 34-5	Employment status among cancer survivors	Letter
van Muijen P	Eur J Cancer Care (Engl) 2013 22(2):144-60	Predictors of return to work and employment in cancer survivors: a systematic review	Review van prognostische factoren
Wells M	Psychooncology 2013 22(6):1208-19	Supporting 'work-related goals' rather than 'return to work' after cancer? A systematic review and meta-synthesis of 25 qualitative studies	Geen review van interventies
Zhang X	Cancer Nurs 2013 36(1):4-5	Cochrane review summary for cancer nursing: interventions to enhance return to work for cancer patients	Bespreking van de Cochrane review van de Boer et al

Search strings Question 1

1. medline (ovid)

1 exp "Patient Acceptance of Health Care"/ (159633)

2 Patient Dropouts/ (6469)

3 complian*.ti,ab. (79272)

4 comply*.ti,ab. (7923)

5 complied.ti,ab. (2692)

6 adher*.ti,ab. (106198)

7 noncomplian*.ti,ab. (5802)

8 nonadher*.ti,ab. (5840)

9 uptake.ti,ab. (235728)

10 (patient adj dropout*).ti,ab. (144)

11 (treatment* adj refusal*).ti,ab. (219)

12 (patient adj participation).ti,ab. (1153)

13 (patient adj acceptance).ti,ab. (2050)

14 maintenance.ti,ab. (172295)

15 variance*.ti,ab. (103492)

16 or/1-15 (821663)

17 Attitude to Health/ or Attitude/ or attitude.ti,ab. (130855)

18 motivation/ or "aspirations (psychology)"/ or drive/ or exploratory behavior/ or goals/ or intention/ or exp personality/ (272618)

19 personality.ti,ab. (49492)

20 behavio?r.ti,ab. (452604)

21 "Social Determinants of Health"/ (46)

22 determinant*.ti,ab. (151108)

23 risk factors/ (543003)

24 exp Socioeconomic Factors/ (329278)

25 predictor*.ti,ab. (187802)

26 social support/ (49664)

27 or/17-26 (1829337)

28 exercise/ or physical conditioning, human/ or resistance training/ or exp running/ or swimming/ or walking/ or exp physical endurance/ or physical fitness/ (133314)

29 exercise movement techniques/ or exercise therapy/ (25219)

30 Movement/ (57861)

31 exp Sports/ (123692)

32 exp "Physical Education and Training"/ (13241)

33 (physical$ adj (active or activity or activities)).ti,ab. (51727)

34 ((MUSCLE or MUSCLES) adj STRENGTHEN$).ti,ab. (461)

35 (SWIM$ or JOG$ or RUN or RUNNING or WALK or WALKING).ti,ab. (154990)

36 ((CIRCUIT$ or RESISTANCE or STRENGTH$ or PHYSICAL or WEIGHT) adj (TRAIN or TRAINING)).ti,ab. (9920)

37 exercise$.ti,ab. (178609)

38 (sport or sports).ti,ab. (33684)

39 aerobic$.ti,ab. (51281)

40 Diet/ or Diet Therapy/ (114787)

41 Nutrition Policy/ or Nutrition Therapy/ (6735)

42 Food Habits/ (20015)

43 (diet or diets or dieta* or diete* or dieti* or nutrition* or food habit* or feeding behavio?r* or eating behavio?r*).ti,ab. (441506)

44 exp Smoking/dt, pc, th [Drug Therapy, Prevention & Control, Therapy] (16352)

45 exp "Tobacco Use Cessation"/ (19909)

46 "Tobacco Use"/pc [Prevention & Control] (5)

47 smoking cessation.ti,ab. (14028)

48 alcohol*.ti,ab. (209186)

49 (binge or drink*).ti,ab. (90807)

50 alcoholism.ti,ab. (23460)

51 exp Drinking Behavior/ (55217)

52 alcohol-related disorders/ or alcoholic intoxication/ or binge drinking/ (13959)

53 exp Body Weight/ (337807)

54 (body adj (weight or mass)).ti,ab. (231700)

55 exp Body Mass Index/ (75735)

56 (body mass index or bmi).ti,ab. (112728)

57 or/28-56 (1607477)

58 exp Neoplasms/ (2500226)

59 Neoplasm Staging/ (117868)

60 cancer$.ti,ab. (977619)

61 tumor$.ti,ab. (894871)

62 tumour$.ti,ab. (191122)

63 carcinoma$.ti,ab. (440172)

64 neoplasm$.ti,ab. (91896)

65 lymphoma.ti,ab. (105058)

66 melanoma.ti,ab. (71051)

67 staging.ti,ab. (47126)

68 metastas$.ti,ab. (204235)

69 metastatic.ti,ab. (130906)

70 exp Neoplasm Metastasis/ (152159)

71 exp neoplastic processes/ (324767)

72 neoplastic process$.ti,ab. (2232)

73 non small cell.ti,ab. (28473)

74 adenocarcinoma$.ti,ab. (89573)

75 squamous cell.ti,ab. (61763)

76 nsclc.ti,ab. (16326)

77 osteosarcoma$.ti,ab. (14066)

78 phyllodes.ti,ab. (1236)

79 cystosarcoma$.ti,ab. (550)

80 fibroadenoma$.ti,ab. (2852)

81 (non adj small adj cell).ti,ab. (28473)

82 (non adj2 small adj2 cell).ti,ab. (28676)

83 (nonsmall adj2 cell).ti,ab. (1675)

84 plasmacytoma$.ti,ab. (5100)

85 myeloma.ti,ab. (34460)

86 multiple myeloma.ti,ab. (22219)

87 lymphoblastoma$.ti,ab. (258)

88 lymphocytoma$.ti,ab. (262)

89 lymphosarcoma$.ti,ab. (3589)

90 immunocytoma.ti,ab. (401)

91 sarcoma$.ti,ab. (68681)

92 hodgkin$.ti,ab. (49979)

93 (nonhodgkin$ or non hodgkin$).ti,ab. (28698)

94 or/58-93 (2879101)

95 16 and 27 and 57 and 94 (1646)

96 limit 95 to yr="2008 - 2014" (740)

2. PreMedline (OVID)

97 complian*.ti,ab. (5839)

98 comply*.ti,ab. (653)

99 complied.ti,ab. (193)

100 adher*.ti,ab. (8530)

101 noncomplian*.ti,ab. (350)

102 nonadher*.ti,ab. (399)

103 uptake.ti,ab. (15519)

104 (patient adj dropout*).ti,ab. (7)

105 (treatment* adj refusal*).ti,ab. (10)

106 (patient adj participation).ti,ab. (100)

107 (patient adj acceptance).ti,ab. (112)

108 maintenance.ti,ab. (11790)

109 variance*.ti,ab. (10666)

110 or/97-109 (51895)

111 attitude.ti,ab. (2386)

112 (motivation or aspiration* or drive or goal* or intention*).ti,ab. (32896)

113 personality.ti,ab. (3335)

114 behavio?r.ti,ab. (68045)

115 determinant*.ti,ab. (8752)

116 risk factor*.ti,ab. (25613)

117 socioeconomic.ti,ab. (3559)

118 predictor*.ti,ab. (16066)

119 social support.ti,ab. (1603)

120 or/111-119 (148731)

121 (physical$ adj (active or activity or activities)).ti,ab. (5548)

122 ((MUSCLE or MUSCLES) adj STRENGTHEN$).ti,ab. (66)

123 (SWIM$ or JOG$ or RUN or RUNNING or WALK or WALKING).ti,ab. (15925)

124 ((CIRCUIT$ or RESISTANCE or STRENGTH$ or PHYSICAL or WEIGHT) adj (TRAIN or TRAINING)).ti,ab. (901)

125 exercise$.ti,ab. (12803)

126 (sport or sports).ti,ab. (4194)

127 aerobic$.ti,ab. (4763)

128 (diet or diets or dieta* or diete* or dieti* or nutrition* or food habit* or feeding behavio?r* or eating behavio?r*).ti,ab. (31337)

129 smoking cessation.ti,ab. (1127)

130 alcohol*.ti,ab. (18816)

131 (binge or drink*).ti,ab. (6138)

132 alcoholism.ti,ab. (917)

133 (body adj (weight or mass)).ti,ab. (16899)

134 (body mass index or bmi).ti,ab. (11875)

135 or/121-134 (99865)

136 neoplasm*.ti,ab. (5465)

137 cancer$.ti,ab. (73743)

138 tumor$.ti,ab. (53329)

139 tumour$.ti,ab. (11056)

140 carcinoma$.ti,ab. (24735)

141 neoplasm$.ti,ab. (5465)

142 lymphoma.ti,ab. (5446)

143 melanoma.ti,ab. (3660)

144 staging.ti,ab. (3178)

145 metastas$.ti,ab. (14682)

146 metastatic.ti,ab. (9555)

147 neoplastic process$.ti,ab. (109)

148 non small cell.ti,ab. (3096)

149 adenocarcinoma$.ti,ab. (5660)

150 squamous cell.ti,ab. (4340)

151 nsclc.ti,ab. (2195)

152 osteosarcoma$.ti,ab. (873)

153 phyllodes.ti,ab. (86)

154 cystosarcoma$.ti,ab. (15)

155 fibroadenoma$.ti,ab. (151)

156 (non adj small adj cell).ti,ab. (3096)

157 (non adj2 small adj2 cell).ti,ab. (3102)

158 (nonsmall adj2 cell).ti,ab. (162)

159 plasmacytoma$.ti,ab. (182)

160 myeloma.ti,ab. (1734)

161 multiple myeloma.ti,ab. (1390)

162 lymphoblastoma$.ti,ab. (12)

163 lymphocytoma$.ti,ab. (12)

164 lymphosarcoma$.ti,ab. (89)

165 immunocytoma.ti,ab. (2)

166 sarcoma$.ti,ab. (4038)

167 hodgkin$.ti,ab. (1975)

168 (nonhodgkin$ or non hodgkin$).ti,ab. (1268)

169 or/136-168 (130134)

170 110 and 120 and 135 and 169 (107)

171 limit 170 to yr="2008 - 2014" (93)

3. EMBASE (via embase.com)

#1	'patient dropouts'/exp OR 'patient compliance'/exp	95566
#2	complian:ab,ti OR comply:ab,ti OR complied:ab,ti OR adher:ab,ti OR noncomplian:ab,ti OR nonadher:ab,ti OR uptake:ab,ti OR (patient:ab,ti AND dropout:ab,ti) OR (treatment:ab,ti AND refusal:ab,ti) OR (patient:ab,ti AND (participation:ab,ti OR acceptance:ab,ti)) OR maintenance:ab,ti	811056
#3	#1 OR #2	854802
#4	'attitude'/de OR 'attitude to health'/exp OR 'behavior'/de OR 'assertiveness'/exp OR 'drive'/de OR 'motivation'/exp OR 'habit'/exp OR 'personality'/exp OR 'social determinants of health'/exp OR 'risk factor'/exp OR 'socioeconomics'/exp OR 'social class'/exp OR 'social support'/exp OR 'predictor variable'/exp	1438822
#5	attitude:ab,ti OR personality:ab,ti OR behavior:ab,ti OR behaviour:ab,ti OR determinant*:ab,ti OR predictor:ab,ti	990540
#6	#4 OR #5	2219091
#7	'exercise'/de OR 'resistance training'/exp OR 'endurance training'/exp OR 'sport'/exp OR 'physical activity'/exp OR 'kinesiotherapy'/de OR 'movement (physiology)'/de OR 'training'/exp	511283
#8	physical:ab,ti AND (active:ab,ti OR activity:ab,ti OR activities:ab,ti) OR (muscle:ab,ti OR muscles:ab,ti AND strengthen:ab,ti) OR swim:ab,ti OR jog:ab,ti OR run:ab,ti OR running:ab,ti OR walk:ab,ti OR walking:ab,ti OR exercise*:ab,ti OR sport:ab,ti OR sports:ab,ti OR aerobic:ab,ti	620565
#9	'diet'/exp OR 'diet therapy'/exp OR 'feeding behavior'/exp	495693
#10	diet:ab,ti OR diets:ab,ti OR dieta:ab,ti OR diete:ab,ti OR dieti:ab,ti OR nutrition:ab,ti OR (food:ab,ti AND habit:ab,ti) OR (feeding:ab,ti AND (behavior:ab,ti OR behaviour:ab,ti)) OR (eating:ab,ti AND (behavior:ab,ti OR behaviour*:ab,ti))	603837
#11	'smoking cessation'/exp OR 'smoking cessation program'/exp OR 'smoking'/de OR 'smoking habit'/exp OR 'tobacco use'/de OR 'tobacco consumption'/exp	235761
#12	smoking:ab,ti AND cessation:ab,ti	21735
#13	'alcohol'/exp OR 'alcoholism'/exp OR 'alcohol abuse'/exp	265310
#14	alcohol:ab,ti OR binge:ab,ti OR drink:ab,ti	383251
#15	'body weight'/de OR 'weight change'/exp OR 'weight control'/exp OR 'weight fluctuation'/exp OR 'weight gain'/exp OR 'weight reduction'/de OR 'body mass'/exp	453958
#16	body:ab,ti AND (weight:ab,ti OR mass:ab,ti) OR bmi:ab,ti	423624
#17	#7 OR #8 OR #9 OR #10 OR #11 OR #12 OR #13 OR #14 OR #15 OR #16	2595551
#18	'neoplasm'/exp	3367194
#19	cancer:ab,ti OR tumor:ab,ti OR tumour:ab,ti OR carcinoma:ab,ti OR neoplasm:ab,ti OR lymphoma:ab,ti OR melanoma:ab,ti OR metastas:ab,ti OR metastatic:ab,ti OR (non:ab,ti AND small:ab,ti AND cell:ab,ti) OR adenocarcinoma:ab,ti OR (squamous:ab,ti AND cell:ab,ti) OR nsclc:ab,ti OR osteosarcoma:ab,ti OR phyllodes:ab,ti OR cystosarcoma:ab,ti OR fibroadenoma:ab,ti OR plasmacytoma:ab,ti OR myeloma:ab,ti OR lymphoblastoma:ab,ti OR lymphocytoma:ab,ti OR sarcoma:ab,ti OR hodgkin:ab,ti OR nonhodgkin*:ab,ti	2771648
#20	#18 OR #19	3798845
#21	#3 AND #6 AND #17 AND #20	2402
#22	#21 AND ([article]/lim OR [article in press]/lim OR [review]/lim) AND ([dutch]/lim OR [english]/lim) AND [2008-2014]/py	827

4. cochrane library (via wiley)

#1 MeSH descriptor: [Patient Acceptance of Health Care] 1 tree(s) exploded

#2 MeSH descriptor: [Patient Dropouts] 1 tree(s) exploded

#3 (complian* or comply* or complied or adher* or noncomplian* or nonadher* or uptake or (patient and dropout*) or (treatment and refusal*) or (patient and (participation or acceptance)) or maintenance):ti,ab

#4 #1 or #2 or #3

#5 MeSH descriptor: [Attitude to Health] 1 tree(s) exploded

#6 MeSH descriptor: [Attitude] this term only

#7 MeSH descriptor: [Motivation] this term only

#8 MeSH descriptor: [Aspirations (Psychology)] this term only

#9 MeSH descriptor: [Drive] this term only

#10 MeSH descriptor: [Exploratory Behavior] this term only

#11 MeSH descriptor: [Goals] this term only

#12 MeSH descriptor: [Intention] this term only

#13 MeSH descriptor: [Personality] 1 tree(s) exploded

#14 MeSH descriptor: [Social Determinants of Health] this term only

#15 MeSH descriptor: [Risk Factors] this term only

#16 MeSH descriptor: [Socioeconomic Factors] explode all trees

#17 MeSH descriptor: [Social Support] this term only

#18 (attitude or personality or behavior or behaviour or determinant or predictor):ab,ti

#19 #5 or #6 or #7 or #8 or #9 or #10 or #11 or #12 or #13 or #14 or #15 or #16 or #17 or #18

#20 MeSH descriptor: [Exercise] this term only

#21 MeSH descriptor: [Physical Conditioning, Human] this term only

#22 MeSH descriptor: [Resistance Training] this term only

#23 MeSH descriptor: [Sports] 1 tree(s) exploded

#24 MeSH descriptor: [Physical Endurance] 1 tree(s) exploded

#25 MeSH descriptor: [Physical Fitness] this term only

#26 MeSH descriptor: [Exercise Movement Techniques] this term only

#27 MeSH descriptor: [Exercise Therapy] this term only

#28 MeSH descriptor: [Movement] this term only

#29 MeSH descriptor: [Physical Education and Training] 1 tree(s) exploded

#30 ((physical* and (active or activity or activities)) or ((muscle or muscles) and strengthen*) or swim* or jog* or run or running or walk or walking or exercise* or sport or sports or aerobic):ab,ti

#31 MeSH descriptor: [Diet] this term only

#32 MeSH descriptor: [Diet Therapy] this term only

#33 MeSH descriptor: [Nutrition Policy] this term only

#34 MeSH descriptor: [Nutrition Therapy] this term only

#35 MeSH descriptor: [Food Habits] this term only

#36 (diet or diets or dieta* or diete* or dieti* or nutrition* or food habit* or (feeding and (behavior* or behaviour*)) or (eating and (behavior* or behaviour*))):ti,ab

#37 MeSH descriptor: [Tobacco Use Cessation] 1 tree(s) exploded

#38 MeSH descriptor: [Tobacco Use] this term only

#39 (smoking and cessation):ti,ab

#40 MeSH descriptor: [Drinking Behavior] 1 tree(s) exploded

#41 MeSH descriptor: [Alcohol-Related Disorders] this term only

#42 MeSH descriptor: [Binge Drinking] this term only

#43 MeSH descriptor: [Alcoholic Intoxication] this term only

#44 (alcohol* or binge or drink*):ti,ab

#45 MeSH descriptor: [Body Weight] 1 tree(s) exploded

#46 MeSH descriptor: [Body Mass Index] 1 tree(s) exploded

#47 ((body and (weight or mass)) or bmi):ti,ab

#48 #20 or #21 or #22 or #23 or #24 or #25 or #26 or #27 or #28 or #29 or #30 or #31 or #32 or #33 or #34 or #35 or #36 or #37 or #38 or #39 or #40 or #41 or #42 or #43 or #44 or #45 or #46 or #47

#49 MeSH descriptor: [Neoplasms] 1 tree(s) exploded

#50 MeSH descriptor: [Neoplasm Staging] this term only

#51 MeSH descriptor: [Neoplasm Metastasis] 1 tree(s) exploded

#52 MeSH descriptor: [Neoplastic Processes] 1 tree(s) exploded

#53 (cancer* or tumor* or tumour* or carcinoma* or neoplasm* or lymphoma or melanoma or metastas* or metastatic or (non and small and cell) or adenocarcinoma* or (squamous and cell) or nsclc or osteosarcoma* or phyllodes or cystosarcoma* or fibroadenoma* or plasmacytoma* or myeloma* or lymphoblastoma* or lymphocytoma* or sarcoma* or hodgkin* or nonhodgkin*):ti,ab

#54 #49 or #50 or #51 or #52 or #53

#55 #4 and #19 and #48 and #54

5. CINAHL

S38	S7 AND S19 AND S34 AND S37	80
S37	S35 OR S36	220159
S36	cancer* or tumor* or tumour* or carcinoma* or neoplasm* or lymphoma or melanoma or metastas* or metastatic or (non and small and cell) or adenocarcinoma* or (squamous and cell) or nsclc or osteosarcoma* or phyllodes or cystosarcoma* or fibroadenoma* or plasmacytoma* or myeloma* or lymphoblastoma* or lymphocytoma* or sarcoma* or hodgkin* or nonhodgkin*	207527
S35	(MH "Neoplasms+")	173590
S34	S20 OR S21 OR S22 OR S23 OR S24 OR S25 OR S26 OR S27 OR S28 OR S29 OR S30 OR S31 OR S32 OR S33	177561
S33	(MH "Body Mass Index")	30377
S32	(MH "Body Weight")	9712
S31	(MH "Binge Drinking")	17
S30	(MH "Drinking Behavior")	629
S29	(MH "Alcoholism") OR (MH "Alcohol Drinking") OR (MH "Alcohol-Related Disorders")	18701
S28	(MH "Smoking Cessation") OR (MH "Smoking Cessation Programs") OR (MH "Smoking")	33030
S27	(MH "Food Habits")	4783
S26	(MH "Nutrition Policy") OR (MH "Nutrition")	14054
S25	(MH "Diet Therapy")	1174
S24	(MH "Diet")	22716
S23	(MH "Therapeutic Exercise")	11177
S22	(MH "Physical Fitness")	7708
S21	(MH "Sports+")	35735
S20	(MH "Exercise") OR (MH "Resistance Training")	21845
S19	S8 OR S9 OR S10 OR S11 OR S12 OR S13 OR S14 OR S15 OR S16 OR S17 OR S18	392541
S18	(MH "Support Psychosocial+")	36935
S17	predictor*	40406
S16	(MH "Independent Variable")	2502
S15	(MH "Socioeconomic Factors+")	166981
S14	(MH "Risk Factors")	59859
S13	determinant*	14044
S12	(MH "Social Determinants of Health")	33
S11	(MH "Goals and Objectives") OR (MH "Goal-Setting") OR (MH "Goal Attainment")	8629
S10	"aspirations"	857
S9	(MH "Motivation") OR (MH "Drive") OR (MH "Personality+") OR (MH "Intention")	96183
S8	(MH "Attitude") OR (MH "Attitude to Health") OR (MH "Health Beliefs")	30105
S7	S1 OR S2 OR S3 OR S4 OR S5 OR S6	94545
S6	complian* or comply* or complied or adher* or noncomplian* or nonadher* or maintenance	73350
S5	"uptake"	11118
S4	"adherence"	16336
S3	(MH "Patient Compliance+") OR (MH "Treatment Refusal")	24820
S2	(MH "Patient Dropouts")	620
S1	"acceptance"	8504

6. PEDRO

Subdiscipline oncology: Abstract & Title

complian*: N=15
comply: N=5
complied: N=0
adher*: N=86
noncomplian*: N=1
nonadher*: N=0
uptake: N=14
dropout: N=8
refusal: N=2
acceptance: N=6
maintenance: N=32

Search strings Question 2

1. medline (ovid)

1 exp Neoplasms/ (2498041)

2 Neoplasm Staging/ (117705)

3 cancer$.ti,ab. (976234)

4 tumor$.ti,ab. (893907)

5 tumour$.ti,ab. (190963)

6 carcinoma$.ti,ab. (439770)

7 neoplasm$.ti,ab. (91812)

8 lymphoma.ti,ab. (104945)

9 melanoma.ti,ab. (70977)

10 staging.ti,ab. (47081)

11 metastas$.ti,ab. (203996)

12 metastatic.ti,ab. (130750)

13 exp Neoplasm Metastasis/ (152011)

14 exp neoplastic processes/ (324415)

15 neoplastic process$.ti,ab. (2230)

16 non small cell.ti,ab. (28431)

17 adenocarcinoma$.ti,ab. (89494)

18 squamous cell.ti,ab. (61682)

19 nsclc.ti,ab. (16298)

20 osteosarcoma$.ti,ab. (14053)

21 phyllodes.ti,ab. (1234)

22 cystosarcoma$.ti,ab. (550)

23 fibroadenoma$.ti,ab. (2852)

24 (non adj small adj cell).ti,ab. (28431)

25 (non adj2 small adj2 cell).ti,ab. (28634)

26 (nonsmall adj2 cell).ti,ab. (1673)

27 plasmacytoma$.ti,ab. (5097)

28 myeloma.ti,ab. (34422)

29 multiple myeloma.ti,ab. (22186)

30 lymphoblastoma$.ti,ab. (258)

31 lymphocytoma$.ti,ab. (261)

32 lymphosarcoma$.ti,ab. (3588)

33 immunocytoma.ti,ab. (401)

34 sarcoma$.ti,ab. (68644)

35 hodgkin$.ti,ab. (49942)

36 (nonhodgkin$ or non hodgkin$).ti,ab. (28671)

37 or/1-36 (2876408)

38 return-to-work.tw. (5270)

39 employment.tw. (33619)

40 unemployment.tw. (6136)

41 unemployed.tw. (4795)

42 retirement.tw. (7735)

43 sick leave.tw. (2995)

44 sickness absence.tw. (1349)

45 absenteeism.tw. (3414)

46 disability management.tw. (194)

47 exp Employment/ (53009)

48 exp Unemployment/ (5058)

49 exp Sick Leave/ (3747)

50 exp Absenteeism/ (7153)

51 exp Work/ (13295)

52 exp Occupations/ (26182)

53 exp Occupational Medicine/ (21660)

54 exp Occupational Health/ (24383)

55 exp Occupational Health Services/ (9554)

56 exp Rehabilitation, Vocational/ (8955)

57 occupation*.tw. (103213)

58 vocational*.tw. (7487)

59 work ability.tw. (680)

60 work capacity.tw. (3783)

61 work activity.tw. (520)

62 work disability.tw. (1257)

63 work rehabilitation.tw. (180)

64 work status.tw. (1175)

65 work retention.tw. (36)

66 workability.tw. (180)

67 employability.tw. (361)

68 employable.tw. (166)

69 employee*.tw. (29493)

70 or/38-69 (282110)

71 37 and 70 (19125)

72 randomized controlled trial.pt. (362054)

73 controlled clinical trial.pt. (87462)

74 randomized.ab. (262574)

75 placebo.ab. (142174)

76 clinical trials as topic.sh. (167631)

77 randomly.ab. (187448)

78 trial.ti. (112531)

79 72 or 73 or 74 or 75 or 76 or 77 or 78 (833512)

80 exp animals/ not humans.sh. (3878559)

81 79 not 80 (765630)

82 meta-analysis.mp,pt. or review.pt. or search:.tw. (1985170)

83 81 or 82 (2634437)

84 71 and 83 (3829)

85 limit 84 to yr="2008 - 2014" (937)

2. PreMedline (OVID)

3 cancer$.ti,ab. (73823)

4 tumor$.ti,ab. (53379)

5 tumour$.ti,ab. (11030)

6 carcinoma$.ti,ab. (24756)

7 neoplasm$.ti,ab. (5448)

8 lymphoma.ti,ab. (5414)

9 melanoma.ti,ab. (3665)

10 staging.ti,ab. (3159)

11 metastas$.ti,ab. (14702)

12 metastatic.ti,ab. (9582)

15 neoplastic process$.ti,ab. (110)

16 non small cell.ti,ab. (3082)

17 adenocarcinoma$.ti,ab. (5663)

18 squamous cell.ti,ab. (4332)

19 nsclc.ti,ab. (2180)

20 osteosarcoma$.ti,ab. (874)

21 phyllodes.ti,ab. (88)

22 cystosarcoma$.ti,ab. (15)

23 fibroadenoma$.ti,ab. (151)

24 (non adj small adj cell).ti,ab. (3082)

25 (non adj2 small adj2 cell).ti,ab. (3087)

26 (nonsmall adj2 cell).ti,ab. (162)

27 plasmacytoma$.ti,ab. (181)

28 myeloma.ti,ab. (1734)

29 multiple myeloma.ti,ab. (1388)

30 lymphoblastoma$.ti,ab. (12)

31 lymphocytoma$.ti,ab. (12)

32 lymphosarcoma$.ti,ab. (89)

33 immunocytoma.ti,ab. (2)

34 sarcoma$.ti,ab. (4044)

35 hodgkin$.ti,ab. (1968)

36 (nonhodgkin$ or non hodgkin$).ti,ab. (1264)

37 or/3-36 (130223)

38 return-to-work.tw. (422)

39 employment.tw. (2491)

40 unemployment.tw. (420)

41 unemployed.tw. (362)

42 retirement.tw. (498)

43 sick leave.tw. (207)

44 sickness absence.tw. (97)

45 absenteeism.tw. (233)

46 disability management.tw. (17)

57 occupation*.tw. (7192)

58 vocational*.tw. (486)

59 work ability.tw. (88)

60 work capacity.tw. (85)

61 work activity.tw. (36)

62 work disability.tw. (75)

63 work rehabilitation.tw. (18)

64 work status.tw. (110)

65 work retention.tw. (5)

66 workability.tw. (31)

67 employability.tw. (32)

68 employable.tw. (10)

69 employee*.tw. (1570)

70 or/38-69 (12739)

71 37 and 70 (718)

72 randomized controlled trial.pt. (608)

73 controlled clinical trial.pt. (68)

74 randomized.ab. (20396)

75 placebo.ab. (7553)

76 clinical trials as topic.sh. (1)

77 randomly.ab. (18269)

78 trial.ti. (8324)

79 72 or 73 or 74 or 75 or 76 or 77 or 78 (43809)

80 exp animals/ not humans.sh. (5)

81 79 not 80 (43809)

82 meta-analysis.mp,pt. or review.pt. or search:.tw. (30886)

83 81 or 82 (71201)

84 71 and 83 (64)

85 limit 84 to yr="2008 - 2014" (54)

3. EMBASE (via embase.com)

#1	cancer:ab,ti OR tumor:ab,ti OR tumour:ab,ti OR carcinoma:ab,ti OR neoplasm:ab,ti OR lymphoma:ab,ti OR melanoma:ab,ti OR metastas:ab,ti OR metastatic:ab,ti OR (non:ab,ti AND small:ab,ti AND cell:ab,ti) OR adenocarcinoma:ab,ti OR (squamous:ab,ti AND cell:ab,ti) OR nsclc:ab,ti OR osteosarcoma:ab,ti OR phyllodes:ab,ti OR cystosarcoma:ab,ti OR fibroadenoma:ab,ti OR plasmacytoma:ab,ti OR myeloma:ab,ti OR lymphoblastoma:ab,ti OR lymphocytoma:ab,ti OR sarcoma:ab,ti OR hodgkin:ab,ti OR nonhodgkin*:ab,ti	2775265
#2	'neoplasm'/exp	3371059
#3	#1 OR #2	3803365
#4	'return to work':ab,ti OR employment:ab,ti OR unemployment:ab,ti OR retirement:ab,ti OR 'sick leave':ab,ti OR 'sickness absence':ab,ti OR absenteeism:ab,ti OR 'disability management':ab,ti OR occupation:ab,ti OR vocational:ab,ti OR 'work ability':ab,ti OR 'work capacity':ab,ti OR 'work activity':ab,ti OR 'work disability':ab,ti OR 'work rehabilitation':ab,ti OR 'work status':ab,ti OR 'work retention':ab,ti OR workability:ab,ti OR employability:ab,ti OR employable:ab,ti OR employee*:ab,ti	245024
#5	'occupation'/exp OR 'unemployment'/exp OR 'work'/exp OR 'occupational medicine'/exp OR 'occupational health'/exp OR 'vocational rehabilitation'/exp	552354
#6	#4 OR #5	662763
#7	#3 AND #6	42812
#8	#7 AND ([cochrane review]/lim OR [meta analysis]/lim OR [randomized controlled trial]/lim OR [systematic review]/lim) AND ([article]/lim OR [article in press]/lim OR [review]/lim) AND ([dutch]/lim OR [english]/lim) AND [2008-2014]/py	352

4. cochrane library (via wiley)

#1 (return-to-work or employment or unemployment or retirement or 'sick leave' or 'sickness absence' or absenteeism or 'disability management' or occupation* or vocational* or 'work ability' or 'work capacity' or 'work activity' or 'work disability' or 'work rehabilitation' or 'work status' or 'work retention' or workability or employability or employable or employee*):ab,ti

#2 MeSH descriptor: [Employment] 1 tree(s) exploded

#3 MeSH descriptor: [Sick Leave] 1 tree(s) exploded

#4 MeSH descriptor: [Absenteeism] explode all trees

#5 MeSH descriptor: [Work] 1 tree(s) exploded

#6 MeSH descriptor: [Occupations] 1 tree(s) exploded

#7 MeSH descriptor: [Occupational Medicine] 1 tree(s) exploded

#8 MeSH descriptor: [Occupational Health] 1 tree(s) exploded

#9 MeSH descriptor: [Occupational Health Services] 1 tree(s) exploded

#10 MeSH descriptor: [Rehabilitation, Vocational] 1 tree(s) exploded

#11 #1 or #2 or #3 or #4 or #5 or #6 or #7 or #8 or #9 or #10

#12 MeSH descriptor: [Neoplasms] 1 tree(s) exploded

#13 MeSH descriptor: [Neoplasm Staging] this term only

#14 MeSH descriptor: [Neoplasm Metastasis] 1 tree(s) exploded

#15 MeSH descriptor: [Neoplastic Processes] 1 tree(s) exploded

#16 (cancer* or tumor* or tumour* or carcinoma* or neoplasm* or lymphoma or melanoma or metastas* or metastatic or (non and small and cell) or adenocarcinoma* or (squamous and cell) or nsclc or osteosarcoma* or phyllodes or cystosarcoma* or fibroadenoma* or plasmacytoma* or myeloma* or lymphoblastoma* or lymphocytoma* or sarcoma* or hodgkin* or nonhodgkin*):ti,ab

#17 #12 or #13 or #14 or #15 or #16

#18 #11 and #17

5. CINAHL

S18	S16 OR S17	38
S17	S15	1
S16	S15	37
S15	S3 AND S14	5839
S14	S4 OR S5 OR S6 OR S7 OR S8 OR S9 OR S10 OR S11 OR S12 OR S13	234633
S13	(MH "Rehabilitation, Vocational")	4197
S12	(MH "Occupational Health") OR (MH "Occupational Health Services")	15192
S11	(MH "Occupational Medicine")	75
S10	(MH "Occupations and Professions+")	49849
S9	(MH "Work")	2721
S8	(MH "Absenteeism")	2427
S7	(MH "Sick Leave")	2454
S6	(MH "Unemployment")	1883
S5	(MH "Employment+")	27794
S4	TX return-to-work or employment or unemployment or retirement or 'sick leave' or 'sickness absence' or absenteeism or 'disability management' or occupation* or vocational* or 'work ability' or 'work capacity' or 'work activity' or 'work disability' or 'work rehabilitation' or 'work status' or 'work retention' or workability or employability or employable or employee*	190323
S3	S1 OR S2	Display
S2	cancer* or tumor* or tumour* or carcinoma* or neoplasm* or lymphoma or melanoma or metastas* or metastatic or (non and small and cell) or adenocarcinoma* or (squamous and cell) or nsclc or osteosarcoma* or phyllodes or cystosarcoma* or fibroadenoma* or plasmacytoma* or myeloma* or lymphoblastoma* or lymphocytoma* or sarcoma* or hodgkin* or nonhodgkin*	Display
S1	(MH "Neoplasms+")	Display

6. PSYCINFO

1 exp Neoplasms/ (33378)

2 cancer$.ti,ab. (37451)

3 tumor$.ti,ab. (9112)

4 tumour$.ti,ab. (1283)

5 carcinoma$.ti,ab. (1192)

6 neoplasm$.ti,ab. (773)

7 lymphoma.ti,ab. (731)

8 melanoma.ti,ab. (526)

9 staging.ti,ab. (1395)

10 metastas$.ti,ab. (905)

11 metastatic.ti,ab. (1024)

12 neoplastic process$.ti,ab. (18)

13 non small cell.ti,ab. (149)

14 adenocarcinoma$.ti,ab. (205)

15 squamous cell.ti,ab. (145)

16 nsclc.ti,ab. (61)

17 osteosarcoma$.ti,ab. (57)

18 phyllodes.ti,ab. (0)

19 cystosarcoma$.ti,ab. (0)

20 fibroadenoma$.ti,ab. (2)

21 (non adj small adj cell).ti,ab. (149)

22 (non adj2 small adj2 cell).ti,ab. (151)

23 (nonsmall adj2 cell).ti,ab. (24)

24 plasmacytoma$.ti,ab. (8)

25 myeloma.ti,ab. (159)

26 lymphoblastoma$.ti,ab. (1)

27 lymphocytoma$.ti,ab. (0)

28 lymphosarcoma$.ti,ab. (7)

29 immunocytoma.ti,ab. (0)

30 sarcoma$.ti,ab. (301)

31 hodgkin$.ti,ab. (559)

32 (nonhodgkin$ or non hodgkin$).ti,ab. (184)

33 or/1-32 (51298)

34 return-to-work.tw. (1606)

35 employment.tw. (37030)

36 unemployment.tw. (6677)

37 unemployed.tw. (4879)

38 retirement.tw. (6934)

39 sick leave.tw. (869)

40 sickness absence.tw. (606)

41 absenteeism.tw. (3058)

42 disability management.tw. (198)

43 exp Employment Status/ (14085)

44 exp Unemployment/ (3103)

45 exp Employee Leave Benefits/ (651)

46 exp Employee Absenteeism/ or exp Employee Attitudes/ (27338)

47 exp "Work (Attitudes Toward)"/ (5430)

48 exp Occupations/ (7341)

49 exp Occupational Health/ (796)

50 exp Vocational Rehabilitation/ (5904)

51 occupation*.tw. (50380)

52 vocational*.tw. (30461)

53 work ability.tw. (585)

54 work capacity.tw. (430)

55 work activity.tw. (501)

56 work disability.tw. (360)

57 work rehabilitation.tw. (182)

58 work status.tw. (800)

59 work retention.tw. (15)

60 workability.tw. (71)

61 employability.tw. (1108)

62 employable.tw. (168)

63 employee*.tw. (46201)

64 or/34-63 (181694)

65 33 and 64 (1278)

66 limit 65 to yr="2008 - 2014" (632)

67 randomized.ab. (36974)

68 placebo.ab. (29643)

69 randomly.ab. (49634)

70 trial.ti. (16816)

71 exp clinical trials/ (7311)

72 meta-analysis.mp,pt. or review.pt. or search:.tw. (72511)

73 67 or 68 or 69 or 70 or 71 or 72 (179795)

74 66 and 73 (54)