Kennisvragen

Gezien de zeer lage bewijskracht, blijft de huidige onderzoeksvraag actueel: What are the beneficial and adverse effects of chemical neurolysis compared to botulinum toxin type A in patients with cerebral and/or spinal spasticity? 

P:	Adults with cerebral or spinal spasticity
I:	Chemical neurolysis of peripheral nerves using phenol or cryoneurolysis (particularly tibialis nerve, obturator nerve)
C:	Botulinum toxin type A
O:	Effects on symptoms, effects on skills and abilities, Duration of effect;, falling, adverse events (neuropathic pain)