Kennislacunes

• What are the effects of hydration versus no hydration in a child receiving intravascular iodine-based contrast media on the risk of PC-AKI and PC-AKI-related complications?

P: Children (<18 years) undergoing radiological examinations with iodine-based contrast media.

I: Hydration with IV NaCl, hydration with IV bicarbonate, oral hydration, hydration, pre- and posthydration.

C: One of the hydration methods described above or no hydration.

O: Post contrast acute kidney injury (PC-AKI), complications of PC-AKI (hospitalization, start of dialysis).

 

• Which eGFR cut-off should be used when identifying children who should receive hydration to prevent PC-AKI?
• Is a sodium bicarbonate hydration strategy to prevent PC-AKI in children receiving intravascular iodine-based contrast media as safe and effective as it is in adults?